1.
Article
in English
| IMSEAR
| ID: sea-161716
ABSTRACT
Aryl / alkyl ketones 1 a-c and 5 a-b were condensed with ethylcyanoacetate or malanonitrile afforded 3 a-c and 7 a-b respectively. Treatment on 3 a-c and 7 a-b with sodium azide and ammonium chloride in presence of dimethylformamide yielded 4 a-c and 8 a-b respectively. All the synthesized compounds have been characterized by the IR, NMR and Mass spectrum spectral data. Compounds 4 a-c and 8 a-b were evaluated for antibacterial activity.