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Article in English | IMSEAR | ID: sea-161716

ABSTRACT

Aryl / alkyl ketones 1 a-c and 5 a-b were condensed with ethylcyanoacetate or malanonitrile afforded 3 a-c and 7 a-b respectively. Treatment on 3 a-c and 7 a-b with sodium azide and ammonium chloride in presence of dimethylformamide yielded 4 a-c and 8 a-b respectively. All the synthesized compounds have been characterized by the IR, NMR and Mass spectrum spectral data. Compounds 4 a-c and 8 a-b were evaluated for antibacterial activity.

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