ABSTRACT
Oral lichen planus (OLP) is a common chronic inflammatory disease of the oral mucosa. The prevalence rate of OLP in adults is 0.5%-2%. The etiology and pathogenesis of OLP are still unclear. The pathogenesis of OLP may be related to the genetic polymorphism of some genes. Currently, the gene families, including tumor necrosis factor, interferon, interleukin, enzyme, and receptor, have been extensively studied. This work reviews related studies on gene polymorphism of OLP.
Subject(s)
Adult , Humans , Lichen Planus, Oral/genetics , Mouth Mucosa , Polymorphism, Genetic , Tumor Necrosis Factor-alpha/geneticsABSTRACT
<p><b>OBJECTIVE</b>To investigate the anatomical features of iliac bone grafts used for mandibular reconstruction and dental implantation.</p><p><b>METHODS</b>Sixteen cadavers were dissected. The length, width, height and cortical thickness of the iliac bone were measured with respect to points determined by the relative dimensions of the bone.</p><p><b>RESULTS</b>The length of iliac bone graft was (77.2 ± 6.1) mm. The height was from (38.2 ± 4.2) mm to (41.9 ± 4.7) mm. The width decreased from iliac crest to base line. The least width 10 mm and 15 mm away from iliac crest were (8.4 ± 2.2) mm and (6.5 ± 2.1) mm respectively. The greatest mean cross-sectional cortical thickness at the intermediate line of the iliac crest was (3.4 ± 0.8) mm.</p><p><b>CONCLUSIONS</b>Anatomical features of iliac bone are suitable for designing bone grafts for mandibular reconstruction followed by dental implantation.</p>
Subject(s)
Humans , Bone Transplantation , Dental Implantation, Endosseous , Methods , Ilium , Transplantation , Mandible , General Surgery , Mandibular Reconstruction , MethodsABSTRACT
Nanocavity biomaterials with recognition specificity imprinted by using proteins as templates may successful serve as substitutes for antibodies, enzymes, and other native biological structures as well as cell bracket materials. It has numerous applications in biotechnology, medicine and so on. In this paper, the principle of template imprinting is introduced briefly, the specialty of template imprinting of proteins is analyzed, and the methods of template imprinting of proteins including protein entrapment, microbead surface imprinting, flat surface imprinting as well as the epitope are reviewed in details.