Molecular biological progress of hepatocyte growth factor (HGF) / 生物工程学报

Hepatocyte growth factor (HGF) is a multifunctional growth factor which is a heterodimeric glycoprotein molecule. There are three truncated HGF variants: NK1, NK2, NK4. The structure of the promoter of HGF is very complicated, and the expression of HGF is regulated by various factors and regulatory elements. Because of the importance of HGF to human body, the genetic engineering expression and gene therapy investigation of HGF are being done.