ABSTRACT
Six new diorganotin [IV] Schiff bases, [[CH3]2SnL] [I], [[C2H5]2SnL] [II], [[n-C4H9]2SnL] [III], [[C6H5]2SnL] [IV], [[CH2C6H5]2SnL] [V] and [[n-C8H17]2SnL] [VI] where L = N-[5-bromo-2 oxidobenzylidene]phenylacetohydrazide, were synthesized and characterized by elemental analysis, FT-IR, multinuclear NMR [1H, 13C] and UV-visible spectroscopy. Spectroscopic studies indicate coordination of ligand to the diorganotin [IV] moieties via ONO donor sites generating a pentacoordinated tin center. The synthesized compounds were tested in vitro for antibacterial activity against Klebsiella pneumonia, Salmonella typhimurium, Escherichia coli, Aeromonas, Staphylococcus aureus, Vibrio cholerae, Pseudomonas aeruginosa, Shigella flexneri, and in vitro antifungal activity against Aspergillus nigar, Fusarium solani, Aspergillus fumigatus and Alternaria species. All the compounds were also screened for antiurease activity
ABSTRACT
To improve the practices of non-physician practitioners on early diagnosis and referral of patients with diabetes mellitus. Study will be conducted in a peri-urban village community in Lahore, Pakistan, during 2007 - 2008. Quasi - experimental study, one group before and after design was used to document the effect of training of non-physician practitioners on improving their diabetic patient identification practices and referral to the hospital for diagnostic and treatment facilities. Fasting blood glucose test was used to identify hyperglycaemics out of those referred by the NPPs. Patient referral was increased by 48.44% after training. Identification of hyperglycaemic patients on the basis of signs and symptoms was 47% before and 48% after training and the difference between two proportions was not significant. increased number of referral showed motivation of NPPs towards the task however more prolonged and structured training program is required to utilize their services in community as part of our health care delivery system