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Ann Natl Acad Med Sci ; 2019 Apr; 55(2): 98-109
Article | IMSEAR | ID: sea-189744

ABSTRACT

Viral encephalitis is inflammation of brain that manifests as neurological complication of viral infections. There are quite a good number of viruses, for example, human herpes virus, Japanese encephalitis, and enteroviruses that can result in such a dreadful condition. Geographical location, age, gender, immune status, and climatic conditions also contribute to the establishment of this disease in an individual. Clinical signs and symptoms include fever, headache, altered level of consciousness, changed mental status, body ache, seizures, nausea, and vomiting. Effective management of this disease relies on timely diagnosis that in turn depends on apt and suitable investigation techniques. Traditional investigations have thinned out these days owing to the fact that advanced molecular technologies have been introduced to the diagnostic field. Treatment of viral encephalitis mainly involves symptomatic relieve from fever, malaise, myalgia along with measures to reduce viral load in the patient. This review mentions about all the possible aspects of viral encephalitis starting from etiology to the management and preventive measures that include immunization and vector control.

2.
Indian J Exp Biol ; 2018 Nov; 56(11): 842-846
Article | IMSEAR | ID: sea-191008

ABSTRACT

Feeding the growing global human population is a tough challenge. Researchers look towards lesser known food crops which are nutritionally adequate, if not superior than the common major crops. Buckwheat (Fagopyrum tartaricum L. Gaerth), also called ‘pseudocereal’, is one such multipurpose crop with promising nutritive value. To enhance utilization of buckwheat as supplement food, here, we did genetic diversity analysis for nutritional parameters. Significant genetic diversity was observed in buckwheat germplasm for 24 nutritional parameters including total oil content (0.75-5.45%), oleic acid (36.98-47.87%), linoleic acid (32.75-44.61%), total protein content (5.65-14.17%), lysine (4.19-8.63 g/16 g N), methionine (0.54-2.48 g/16 g N) and half cystine (0.82-3.57 g/16 g N). The entire germplasm was grouped into three clusters. Cluster I comprised accessions promising high oil, stearic acid, oleic acid, least in linoleic acid and essential amino acids. Cluster II had accessions promising quality oil with highest linoleic acid and linolenic acid (PUFA) and highest half-cystine and glycine. Cluster III possesed promising accessions for highest oil percent, total protein, high essential amino acids and highest test weight. The inter-simple sequence repeats (ISSR) analysis using 26 primers indicated significant genetic diversity existed at molecular level. This study includes large number of accessions analyzed for nutridiversity in entire spectrum of germplasm collections of the world. Nutritionally rich promising genotypes identified will be potential genetic stocks for making buckwheat, a prospective supplement food crop.

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