ABSTRACT
An unusual case of mixed adenoneuroendocrine carcinoma is described which posed a diagnostic challenge in view of neuroendocrine component mimicking signet ring cells of adenocarcinoma. Diagnostic criteria for these mixed tumors, their histogenesis and treatment modalities are highlighted.
ABSTRACT
Background: Malignant rhabdoid tumors of kidney are associated with atypical teratoid rhabdoid tumors of brain, both being characterized genetically by deletion/ mutation of SMAR CBI/ INI gene. Case characteristics: 6-month-old male presented with a brain tumor and was subsequently found to have malignant rhabdoid tumor of kidney. Interventions: Surgical resection of brain tumor followed by chemotherapy and subsequently resection of renal tumor. Outcome: Child died seven months after initial presentation. Message: Children presenting with embroynal brain tumor, should be investigated for renal tumors and vice versa.