ABSTRACT
Background: Homocysteine is an amino acid which has sprung into prominence in the past few decades. Levels of maternal serum homocysteine normally decreases with gestation, either due to a physiological response to the pregnancy, increase in estrogen, haemodilution from increased plasma volume or increased demand for methionine by both the mother and fetus.Methods: A prospective randomized controlled clinical trial of 50 patients was carried out in Kamla Raja Hospital and outpatient Department of Gajra Raja Medical College, Gwalior from October 6th to October 2007, which was further categorized into socio-demographic and clinical factors.Results: Out of 50 patients, it was found that there were 31(62%) cases below the age of 25 years whereas 19(38%) cases were above the age of 25 years, 30(60%) cases were educated below the primary level whereas 20(40%) cases were educated above the primary level, 10(20%) cases belonged to rural areas whereas 40(80%) cases belonged to the urban areas. According to the socio economic distribution, 11(22%) cases were below class II whereas 39(78%) cases were above class II. According to distribution of parity, 22(44%) cases were below primigravida whereas 28(56%) cases were above primigravida.Conclusions: This study concludes that mean of Serum Levels in pregnant women with socio-demographic and clinical factors was statistically insignificant which signifies that age, education, residential areas and hemoglobin are not the factors contributing to the rise in homocysteine level in pregnant women. The diastolic and systolic blood pressure is weakly correlated with serum homocysteine level.
ABSTRACT
Background: Hypertensive disorders in pregnancy (HDP) remain a major global health issue not only because of the associated high adverse maternal outcomes but there is a close accompaniment of significant perinatal morbidity. Intrauterine growth restriction (IUGR), a condition that occurs due to various reasons, is an important cause of fetal. It has been defined as a rate of fetal growth that is less than normal in light of the growth potential of that specific infant. The aim of this study is to evaluate the prevalence and risk factor for IUGR among the PIH patient.Methods: A prospective randomized controlled clinical trial of 25 patients was carried out in Kamla Raja Hospital and Out Patient Department of Gajra Raja Medical College, Gwalior from October 6th to October 2007. A total number of 25 patients were included in study of PIH.Results: conclude that the prevalence and risk factor for IUGR among the PIH patient. The Distribution prevalence of sociodemographical factor for IUGR among PIH patient is statistically not significant. It concluded that there is no significance (no effect) between risk factors of IUGR among the pregnancy induced hypertension.Conclusions: The prevalence of IUGR found in this study. There is need to increase awareness among medical and paramedical personnel on the need for early referral of women with previous history of IUGR, preeclampsia, multiple gestations, gestational diabetes and obesity for specialist care as they have a higher risk.
ABSTRACT
Background: Iodine is an important micro-nutrient required for human nutrition. Iodine Deficiency Disorders (IDDs) are one of the major world-wide public health problems of today which causes wide spectrum of disabilities. It includes impairment of reproductive functions, lowering of IQ levels in school age children, goiter, deaf mutism, mental defects, weakness and paralysis of muscles as well as lesser degree of physical dysfunction. Methods: Selection of population: The school children in age group of 6-18 years from both the sexes were screened from SGRR Schools of different locations at Dehradun, after taking approval from principal and the parents. Results: The prevalence of goitre among school going children was 5%. Prevalence of goitre among female was 6.4% compare to male were 4.1%. There was significant association found between prevalence of goitre and vegetarian diet. In pre pubertal age (11-14 years) maximum (7.6%) cases of goitre were seen. A significant association of goitre with pallor was also observed Conclusion: The sustained efforts in implementing the guidelines of National Iodine Deficiency Disorders Control Programme (NIDDCP) have been able to reduce the prevalence of goitre in Uttrakhand state. In spite of reduction in prevalence over years, goitre continues to be a major public health problem in the state.