Studies on chemical constituents of the marine sponge Topsentia sp. from the South China Sea / 中国海洋药物

Six organic compounds were isolated from the marine sponge Topsentia sp. collected from the South China Sea. Their chemical structures were identified by 1H-NMR, 13C-NMR,IR,MS and GC-MS as cholesterol(Ⅰ); 24-ethylidenecholest-5-en-3?-ol(Ⅱ); phenylacetic acid(Ⅲ); 4-hydroxybenzaldehyde(Ⅳ);indole-3-carboxaldehyde(Ⅴ); thymine(Ⅵ).

Natural nitrogenous compounds from the South China Sea marine sponge Clathria fasciculate / 中国海洋药物

Objective To study the bioactive chemical constituents of the marine sponge Clathria fasciculate which collected from the South China Sea.Methods Using organic solvent for crude extraction and column chromatography for further isolation. Chemical structures were identified on the basis of spectrum data of ~(1)H-NMR, ~(13)C-NMR, IR, UV and MS. The stereochemistry was determined by comparing optical rotation values with authentic data. Results and Conclusion Six nitrogenous organic compounds were elucidated as adenosine(Ⅰ), uridine(Ⅱ), thymidine(Ⅲ), hypoxanthine(Ⅳ), thymine(Ⅴ) and uracil(Ⅵ) which were obtained from the (n-butanol) extract.