ABSTRACT
Objectives: to study the clinical features of chronic arsenicosis on usage of arsenic contaminated ground water among the residents of Pathalkudwa mohalla, Ranchi district
Material and Methods: a cross-sectional observational study was done on 39 patients, all residents from Pathalkudwa mohalla, Ranchi, clinically suspected of arsenic toxicity attending the department of dermatology of a tertiary care centre over a period of one year. Arsenic levels estimation was done in drinking water, urine, hair and nails. Cutaneous markers like hyperpigmentation over trunk, palmoplantar keratosis and Aldrich's Mees lines were included. Non-residents of Pathalkudwa mohalla were excluded from the study
Results: among of 39 cases affected by arsenic contamination, 20 [51.3%] cases were females and 19 [48.7%] were males. Most of the women were housewives by occupation followed by office job persons and students. Among various clinical features, tingling and numbness of extremities [84%] were the most common complaint followed by weakness [79%] and pain abdomen [74%]. Palmoplantar keratosis [90%] was seen in majority of patients followed by raindrop pigmentation [48%], diffuse hyperpigmentation [28%] and Aldrich Mee's lines [3%]. No signs of cutaneous malignancy was seen in any of the patient
Conclusion: hyperkeratosis of palms and soles and skin hyperpigmentation were the most common cutaneous manifestations of chronic arsenicosis
ABSTRACT
Objective: To study the prevalence and the pattern of mucocutaneous manifestations among diabetic patients to aid in better management of diabetic skin diseases
Methods: Three hundred consecutive patients with the diagnosis of diabetes mellitus [DM] and seeking treatment for skin lesions in the OPD of Department of Dermatology in Rajendra Institute of Medical Sciences, Ranchi were included in the study
Results: Diabetic patients accounted for 7.2 percent of Dermatology OPD attendance with a male preponderance [M:F=1.4:1]. The common skin disorders for which patients sought treatment were: superficial fungal infections [24 percent], acrochordons [17.7 percent], xerosis [13.7 percent] and bacterial infections [7.4 percent]
Conclusion: Skin problems are quite common among diabetic population. Most of the dermatoses were infectious in nature. The early detection of mucocutaneous manifestations in DM is of utmost importance to be able to avoid and manage the complications and prevent disability
ABSTRACT
Xanthomas are focal infiltrates of lipid-containing histiocytic foam cells that are usually found within the dermis or tendons. It is a clinical manifestation of lipoprotein metabolic disorders. We report a case of tuberous xanthoma in a 45-year-old woman who presented with multiple firm papules and nodules involving multiple sites of the body/including the amputated right forearm with elevated serum cholesterol, triglycerides, LDL arid VLDL
ABSTRACT
Epidermodysplasia verruciformis [EV] is a rare genodermatosis characterized by a unique susceptibility to cutaneous infection by a group of phylogenetically related human papilloma viruses [HPVs]. These patients show a defect in cell-mediated immunity specific toward the causative HPVs that leads to lifelong disease. The defect is usually inherited as autosomal recessive trait and presents clinically with plane warts, pityriasis versicolor-like lesions and reddish verrucous plaques. Dysplastic and malignant changes in the form of actinic keratoses, Bowen's disease and squamous cell carcinoma [SCC] are common but metastasis occurs rarely. A totally effective treatment against EV is as yet highly desirable. We report a case of EDV in a 13-year-old female patient with confluent wart like lesions, pityriasis versicolor like lesions and reddish plaques. The case is being reported in view of rarity of disease