A Clinical Study of Oral Mucosal Changes Adjacent to Amalgam Restorations

@#Amalgam has been widely used in dentistry and its components may cause some oral mucosal changes (OMC), commonly presenting as oral lichenoid lesions (OLLs), acute or generalized sensitivity reaction or amalgam tattoo. Our objective was to determine the demographic and clinical profile of patients with and without OMC adjacent to their amalgam restorations (AR) and to evaluate the prevalence and types of AR-related OMC and associated clinical parameters.Materials and methods: In this retrospective cross-sectional study, 83 outpatients attending the Primary Dental Care Unit at the Faculty of Dentistry, University Malaya wereexamined for the presence of AR-related OMC. The studyperiod was from early to mid July 2016. Firstly, patients’ personal details (age, gender, medical status, social habits) were analyzed and history of AR (the age, condition and number of restorations) was determined. Clinical examination of patient’s oral cavity was carried out to detect any AR-related OMC. The data collected was analyzed using SPSS 12.0.1 Result: Approximately 14.6 % patients had OMC. OLLs and amalgam tattoo made up 1.2% and 13.4% respectively. Females (8.4%) had higher predilection and Chinese were more commonly affected (8.4%). Social habits were not associated with OMC. Certain systemic diseases, age (p=0.005) and duration of amalgam (p=0.007) in the oral cavity were significant risk factors for OMC. Conclusions: Present findings suggest that AR-related OMC is uncommon. Three key parameters namely systemic diseases, patient’s age and duration of AR were identified as significant risk factors predisposing to the development of OMCs.

Solitary parotid duct sialolith in a patient with Sjörgren’s syndrome: Report of a case

@#Sjörgren’s syndrome is an uncommon chronic autoimmune disorder that affects exocrine glands. Sialolithiasis is an obstructive salivary gland disease which is also uncommon in the parotid salivary gland. The existing literature has documented the occurrence of multiple calcifications within the parenchyma of the parotid glands in patients with Sjörgren’s syndrome. This report describes the first case of right parotid duct solitary sialolith formation in a 64 year old female patient with Sjörgren’s syndrome. Whether the salivary stone encountered in this case represents an oral manifestation of Sjörgren’s syndrome or is just a co-incidental finding was discussed.

A Preliminary Clinical Study Of Lesion-Free And Lesion-Active Patients With Oral Lichen Planus And/Or Oral Lichenoid Reactions

Background: Oral lichen planus (OLP) which belongs to the spectrum of LP, is a commonly encounteredoral mucosal problem among patients seeking treatment in the Oral Medicine clinic. Its counterpart, orallichenoid reaction (OLR), which resembled OLP clinically and microscopically, is often encountered inthese patients as well. Although the various clinical forms of OLP/OLR are well-recognized, the diseasepattern in regards to lesion-active and lesion-free periods in these patients remains poorly characterized.Thus the aim of this study was to determine the clinical and demographic profile of those patients withactive OLP/OLR lesions and compare them with those patients who are clinically lesion-free.Materials and methods: The study subjects comprised 20 patients who attended the Oral MedicineClinic at the Faculty of Dentistry, University of Malaya for follow-up appointments/management. Theywere interviewed according to a pre-designed questionnaire, and clinical examination was carried out. Allthese were conducted under the supervision of Oral Medicine specialists. OLP was diagnosed accordingto the internationally accepted criteria.Results: The cohort consisted of predominantly female (n=14; 70%) and Chinese (n=9; 45%) patients,with an overall age range of 26-79 years (median, 56 years). Fifteen (75%) patients presented withactive OLP/OLR lesions and the remaining 5 (25%) were lesion-free. The lesion-active group comprised3 (15%) males and 12 (60%) females whereas the lesion-free had 3 (15%) males and 2 (10%) females.Reticular LP was the most common type (n=21/35; 60%) and the gingiva was the most prevalent site(n=21/46; 45.65%). Social habits, medical histories and medications were not significantly differentbetween lesion-active and lesion-free OLP patients.Conclusions: Findings suggest that demographic parameters, lifestyle and systemic diseases do notappear to influence the disease pattern and lesion severity in OLP.