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Acta Pharmaceutica Sinica B ; (6): 1315-1328, 2021.
Article in English | WPRIM | ID: wpr-881201

ABSTRACT

Bcr-Abl threonine 315 to isoleucine 315 (T315I) gatekeeper mutation induced drug resistance remains an unmet clinical challenge for the treatment of chronic myeloid leukemia (CML). Chemical degradation of Bcr-Abl

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