ABSTRACT
Aim: This study aimed to compare the microbiological potential and gustatory perception of essential oils (EO) mouthrinses containing and not containing alcohol. Methods: Twenty healthy adult volunteers rinsed with 10mL of the following test solutions: EO with alcohol, EO without alcohol, or a control solution (saline solution with mint essence). A washout period of at least seven days was adopted after a single-use protocol of the respective solution. All participants used all three tested substances. Antimicrobial potential was assessed by counting salivary total viable bacteria both before and after each rinse. Gustatory perception was evaluated using the Visual Analogue Scale (VAS). Multiple comparisons were performed with the Wilcoxon test, using Bonferroni correction. Results: Both EO solutions presented a higher antimicrobial potential in comparison to the control solution (p<0.017). However, no significant difference in antimicrobial potential was observed between EO containing or not containing alcohol (p=0.218). VAS of EO with alcohol (median: 2.7) was similar to control solution (median: 1.6) (p=0.287). A better gustatory perception was observed of the EO without alcohol (median 7.6) when compared to the control solution (p<0.0001). When EO groups were compared, EO without alcohol also demonstrated a significantly better gustatory perception (p=0.001). Conclusion: Mouthrinse containing EO without alcohol presented a better taste perception when compared to the EO with alcohol, but no difference was observed in the antimicrobial potential of both EO solutions after a single rinse protocol
Subject(s)
Humans , Male , Female , Bacteria , Oils, Volatile , Alcohols , Taste Perception , MouthwashesABSTRACT
A Assistência Farmacêutica no Brasil é dividida em Componente Básico, Especial, Especializado e Estratégico. Para fornecimento do medicamento pelo Componente Especial e/ou Especializado, que segue os Protocolos Clínicos e Diretrizes Terapêuticas do Ministério da Saúde, exige-se a abertura de processo administrativo, juntamente à Farmácia de Medicamentos Especiais do Estado do Rio Grande do Sul. A demanda de processos administrativos, para obtenção desses medicamentos é grande e não foram encontrados estudos sobre os desfechos dos encaminhamentos desses processos. O objetivo do presente estudo foi analisar o desfecho dos encaminhamentos dos pacientes com demanda de medicamentos do componente Especial e/ou Especializado da Assistência Farmacêutica. Trata-se de um estudo transversal, realizado em uma unidade de Atenção Primária à Saúde, no período de 2013 a 2014. Foram aplicados questionários aos pacientes e/ ou responsáveis, que se consultaram no ambulatório de Farmácia, requerendo medicamentos junto à Farmácia de Medicamentos Especiais. Os principais resultados indicam que 12 pacientes (75%) tiveram o processo totalmente deferido, sendo que 8 pessoas (50%) levaram até 1 mês para resposta do processo administrativo. A renda média familiar da amostra foi de 2500 reais com um gasto médio de 100 reais por família, representando o gasto com medicamento 4% da renda familiar. Os desfechos dos encaminhamentos dos usuários da Atenção Primária à Saúde foram considerados resolutivos, sendo que a orientação ao paciente, no ambulatório farmacêutico, mostrou-se efetiva em relação a esses encaminhamentos.
Pharmaceutical Care in Brazil is divided into Basic, Special, Specialized, and Strategic Components. For the supply of medication by the Special and/or Specialized Component that follows the Clinical Protocols and Therapeutic Guidelines of the Ministry of Health, an administrative process must be opened together with the Special Medications Pharmacy of the State of Rio Grande do Sul. The demand for administrative processes to obtain these drugs is great and we did not find studies on the outcomes of the referrals of these processes. The objective of the present study was to analyze the outcome of the referrals of patients with the need for medications from the special and/or specialized component of Pharmaceutical Care. This is a cross-sectional study carried out in a primary healthcare unit from 2013 to 2014. Questionnaires were administered to patients and/or caregivers who visited the Pharmacy clinic requesting medication from the Special Medications Pharmacy. The main results indicate that 12 patients (75%) had the procedure totally deferred, with 8 people (50%) waiting up to 1 month for a response on the administrative process. The mean family income of the sample was 2,500 Brazilian reais (BRL), with a mean expenditure of 100 reais per family, representing a medication expenditure of 4% of family income. The outcomes of referrals of Primary Health Care users were considered as effectively resolved, with patient orientation in the pharmaceutical outpatient clinic having proved effective in relation to these referrals.