ABSTRACT
To estimate the frequency of anti-Toxocara sp. antibodies, and evaluate factors associated with this infection, sera from 242 male and female children, aged from one to fifteen years old, attended at the Hospital of the Federal University of Uberlândia, Minas Gerais State, Brazil, were analyzed by ELISA. Information on the patients was collected and registered using an investigative questionnaire, and details on possible clinical alterations were obtained from the medical charts of 187 patients. Of a total of 242 samples, 21 (8.7 percent) were positive for anti-Toxocara sp. antibodies. The presence of dogs and cats and the school variable (place of contact), appeared to be significantly associated (p < 0.05) with a positive serology. Respiratory symptoms and eosinophil counts greater than 20 percent also showed a positive statistical correlation with a positive serology for Toxocara sp. Factors such as sex and age, and symptoms like headache, stomach ache, convulsive crises and anemia were not associated with toxocariasis.
Para determinar a frequência de anticorpos anti-Toxocara sp. e os fatores de risco associados à infecção, soros de 242 crianças de ambos os sexos, com idade entre um a 15 anos, atendidas no ambulatório do Hospital da Universidade Federal de Uberlândia, Minas Gerais, Brasil, foram analisados pelo ELISA. Questionários foram aplicados, para obter informações sobre os pacientes. As informações sobre as alterações clínicas, de 187 pacientes, foram obtidas no prontuário médico. Do total das 242 amostras, 21 (8,7 por cento) foram positivas para anticorpos anti-Toxocara sp.. A presença de cães e gatos e a variável escola (local de contato) sugerem associação significativa (p < 0.05) com a sorologia positiva. Sintomas respiratórios e elevada contagem de eosinófilos (> 20 por cento) mostram correlação positiva com a soropositividade para Toxocara sp.. A idade, sexo, sintomas como dor de cabeça, dor estomacal, crises convulsivas e anemia não apresentaram associação com toxocaríase.