ABSTRACT
Onychomycosis due to Fusarium species almost always involves the great toe nails, especially those affected by traumatic and dystrophic abnormalities. The combination of proximal subungal onychomycosis with subacute or acute paronychia is the typical finding of nail disease due to Fusarium species. The patient was a 12-year-old Korean boy who presented with tenderness and onychoschizia of right great toenail and painful, erythematous swelling and vesicles on periungual area of the right great toe for 10 days. The patient has been healthy except marked growth retardation of both great toe nails with familian backgrounds. Direct microscopic examination of scraping on the potassium hydroxide preparation revealed fungal elements and repeated cultures on Sabouraud dextrose agar showed the same white colonies. Slide culture revealed abundant, oval shaped microconidia and three to five septated, sickle-shaped macroconidia, which was consistent with Fusarim oxysporum. The nail symptoms showed good response to the systemic therapy with terbinafine 250 mg daily. He is now under observation after 3 months of the systemic therapy.
Subject(s)
Child , Humans , Male , Agar , Fusarium , Glucose , Nail Diseases , Nails , Onychomycosis , Paronychia , Potassium , ToesABSTRACT
Onychomycosis due to Fusarium species almost always involves the great toe nails, especially those affected by traumatic and dystrophic abnormalities. The combination of proximal subungal onychomycosis with subacute or acute paronychia is the typical finding of nail disease due to Fusarium species. The patient was a 12-year-old Korean boy who presented with tenderness and onychoschizia of right great toenail and painful, erythematous swelling and vesicles on periungual area of the right great toe for 10 days. The patient has been healthy except marked growth retardation of both great toe nails with familian backgrounds. Direct microscopic examination of scraping on the potassium hydroxide preparation revealed fungal elements and repeated cultures on Sabouraud dextrose agar showed the same white colonies. Slide culture revealed abundant, oval shaped microconidia and three to five septated, sickle-shaped macroconidia, which was consistent with Fusarim oxysporum. The nail symptoms showed good response to the systemic therapy with terbinafine 250 mg daily. He is now under observation after 3 months of the systemic therapy.
Subject(s)
Child , Humans , Male , Agar , Fusarium , Glucose , Nail Diseases , Nails , Onychomycosis , Paronychia , Potassium , ToesABSTRACT
Scedosporium apiospermum is the asexual stage of Pseudallescheria boydii that is ubiquitous in nature. The localized cutaneous abscess due to S. apiospermum is rare and it is usually originated from the traumatic inoculation of fungal elements. We report a case of cutaneous abscess caused by S. apiospermum. A 67-year-old woman presented with one-year history of subcutaneous nodules on the left forearm, which had been misdiagnosed as cutaneous tuberculosis. Cultural isolation for definitive diagnosis showed typical S. apiospermum.