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This systematic review (SR) synthesises recent evidence and assesses the methodological quality of published SRs in the Differential diagnosis of temporomandibular disorders (TMD). A systematic literature search was conducted in the PubMed, Cochrane Library, and Bandolier databases for 1987 to September 2019. Three investigators evaluated the methodological quality of each identified SR using two measurement tools: The assessment of multiple systematic reviews (AMSTAR) and level of research design scoring. Thirty-one SRs met inclusion criteria and 28 were analysed: 20 qualitative SRs and eight meta-analysis.The main aim of this article is to Differential diagnose the pain which is not related to any dental disease. Most of dental clinician have problem to diagnose TMD (Temporomandibular Disorders) and Orofacial Muscle pain. The approach of this article is to simplify the differential diagnosis for better and fast treatment of the respective disease by classifying various TMJ related and muscle related problems
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Background: Ovarian cancers represent the 6th most common cancer among females and are the most common cause of death from gynaecological cancers in the world. The aim is to do clinicopathologic study of ovarian tumours along with evaluation of the expression of estrogen receptor (ER) and human epidermal growth factor receptor (HER2/neu).Methods: A total of 85 cases of ovarian tumors were studied and immunohistochemistry was performed with specific antibodies against ER and HER2/neu as per standard protocol.Results: In present study, surface epithelial tumours were the commonest type comprising 64 cases (75.2%), followed by Germ cell tumours, 17cases (20%) and sex cord stromal tumours, 04 cases (4.8%).Among the surface epithelial tumours , ER‑positive cases were higher in malignant (71.4%) tumours as compared to borderline tumours (33.3%) and benign tumours (7.7%) while Her2/neu positive cases were higher in borderline (66.7%) tumours as compared to malignant tumours (42.9%) and benign tumours (15.3%).Among the germ cell tumours, ER expression was positive in 62.5% cases of mature teratoma while HER2/neu expression was positive in only 12.5% cases of mature teratoma. None of the sex cord stromal tumours showed positive expression of ER and HER2/neu.Conclusions: Positive expression of estrogen receptors is seen predominantly in surface epithelial malignancies and in mature teratoma. It proves the mitogenic role of estrogen in ovarian tumours. Her-2 neu was expressed mainly in malignant tumours. This suggests their carcinogenic role. This also helps in differentiating borderline and malignant tumours.
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As urbanisation is increasing, the problem of communicable as well as non-communicable diseases (NCDs) is also increasing. Hypertension, diabetes, obesity, cardiovascular diseases constitute most of the NCDs whose risk factors are almost similar. They could be modifiable like physical activity, waist circumference, diet, smoking, alcohol intake . Objective: To study the magnitude of shared risk factors for Non-communicable diseases in adults of an urban resettlement colony of Delhi. Material and Methods: A cross sectional survey was conducted on adults >30 years (n=580) in both genders in an urban resettlement colony of Delhi in 2014. A Semi-structured interview schedule consisting of Socio-demographic characteristics, risk factor profile was used. Data was entered and analyzed in SPSS 12 Results: Out of the total 580 subjects (313)53.96% were women and 267(46.03%) were men. Majority 405(69.8%) of the study subjects were taking inadequate fruits and vegetables (<5 times/day) and 212 (36.6%) were taking >5 gm salt per day. About 181(31.2%) of the study subjects were sedentary workers, the proportion was more among women 99(31.6%). 223(83.5%) men had waist circumference within normal limits whereas 178 (56.9%) women had waist circumference more than 88 cm. One in four men were smokers. Nearly 49(18.4 %) of the men were current tobacco chewers as compared to 17(1.6%) of women. Only 33 (12.4%) men were currently consuming alcohol. Results of multiple logistic regression showed increasing age, education and marital status as significant socio demographic factors for increased prevalence of risk factors for NCDs. Conclusion: Promotion of lifestyle change to address these risk factors that can be modified including weight reduction, increased physical activity and healthy eating should be encouraged along with changing of behavioural factors like quitting smoking and alcohol.
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Background: Aim of current study was to know the etiological factors of jaundice among pregnant patients, outcome and their management. Methods: A retrospective study done at IMS, BHU in obstetrics and gynecology department among pregnant patients with jaundice admitted in obstetric wards and labour room in six months duration. Results: Among total 1960 admissions, 78 (3.97%) patients presented with jaundice. Out of all admissions 27 (1.37%) were HBSAg, 8 (0.40%) HEV, 7 (0.35%) HCV, 6 (0.30%) of HBSAg and HEV co-infection, cholestasis with pregnancy 20 (1%) and 10 (0.51%) patients with pre-eclamptic liver disease with HELLP. Conclusions: Jaundice in pregnancy may be lethal to mother and fetus. As the course of disease is also rapid and in short period it may affect the fetus in utero also, early detection and prompt management of these cases should be done.
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Background: Cervical cancer still remains a leading cause of morbidity and mortality among women worldwide. Despite attempts to increase screening over the past several decades, incidence and mortality rates of cancer cervix have not shown substantial reduction. The conventional method of screening by cervical cytology/pap smear has failed to reduce the disease burden due to lack of patient compliance for repeated testing and a relatively sophisticated infrastructure. Therefore, alternative methods such as visual inspection after application of acetic acid (VIA), visual inspection with Lugol's Iodine (VILI) and human papillomavirus (HPV) DNA testing have been developed. The aim of present study was to compare Pap smear and VIA and evaluate their usefulness as tools for screening of premalignant and malignant lesions of cervix. Methods: This was a crossectional study over 5 months from 1 Jan 2015 to 31 may 2015 in which 212 patients attending the obstetrics and gynecology department, BHU were enrolled. Pap smear was taken followed by VIA. Pap smears were sent to pathology department, BHU where they were reported as per Bethesda System, 2001. Cervical biopsies were done in positive cases. Data obtained and statistically analyzed. Results: The present study was conducted over a period of 6 months among 212 patients age of 18-60 years screened. Positive results obtained from cytology were 26, VIA was positive in 28 women. Cervical biopsy was done in 34 women who had positive results by either test. Histology in 31 cases was suggestive of cervical intraepithelial carcinoma (CIN). Conclusions: VIA, though less specific has comparable sensitivity to Pap smear and may be used as a primary screening tool for cervical cancer. In combination both the tests have a higher predictive accuracy.