ABSTRACT
Background: Carcinoma gallbladder is a major problem in India. In this retrospective study from the tertiary care centre of the north–east India, we aim to review the various Multidetector Computed Tomography (MDCT) imaging findings of gallbladder carcinoma. Methods: We retrospectively analysed MDCT findings in 65 biopsy proven cases of gallbladder carcinoma. After administration of oral contrast for bowel opacification, all patients were subjected to non–contrast scan of the upper abdomen followed by contrast enhanced study of the abdomen and pelvis in the portal venous phase. Results: Focal mass lesion arising from gallbladder was the predominant pattern of growth seen in 31(48%) patients followed by focal or asymmetric diffuse wall thickening in 28(43%) patients. Twelve (18%) patients had mass in gallbladder fossa replacing the gall bladder. Adjacent hepatic infiltration was seen in 48(74%) patients. Conclusion: Our study highlights the importance of MDCT for the diagnosis, characterisation and staging of gallbladder carcinoma.
ABSTRACT
Primary mediastinal seminomas are rare tumors. Morphologically, they can be associated with secondary changes in the form of thymic remnants, cystic change, epithelioid granulomas, abundant fibrosis, and syncytiotrophoblast like cells. Ours was an interesting case where a 17‑year‑old adolescent male presented with anterior mediastinal mass. Fine needle aspiration and trucut biopsy of the mass favored tuberculosis; however, he did not respond to antituberculosis treatment regime. He was subjected to video‑assisted thoracoscopic surgery and the histopathological examination along with supportive immunohistochemistry of the mass revealed scattered seminoma cells which were being masked by extensive granulomatous reaction. The aim of this article is to report a case of primary mediastinal thymic seminoma in a young male associated with extensive granulomatous reaction masking the neoplastic population of cells leading to erroneous diagnosis on small biopsy.