ABSTRACT
Background: The uric acid in serum (SUA) is significantly related with cardiovascular disease, it is proved by clinically. The increased level of uric acid in the serum lead to highly platelet reactivity mediating inflammation and stimulate of smooth muscle cell production which probably degrades acute thrombosis. Methods: The blood samples were collected and sent to biochemistry laboratory for estimation of uric acid. This study conducted in the Departments of Biochemistry, Dr. Ram Manohar Lohia Medical College Lucknow. Results: In this study 200 patients included with acute myocardial infarction. Among the 200 patients, 148 (74%) were male and 52 (26%) were female. Among the 25-70 Age group , most of people from 56-70 age group. Mean of uric acid level in male cases was 5.6 and female cases was 5.2 , male controls was 4.2 and female controls was 3.6. Conclusion: The uric acid level in the serum are high in patients which had acute myocardial infarction as compare to other persons. It is also higher with the killips classes. The Killips classification and uric acid level in the serum is a good analyst of mortality after acute myocardial infarction, if is combined.