Prevalence of mental health problem during first-half pregnancy at Siriraj Hospital.

OBJECTIVE: To study the prevalence of mental health problem during first-half pregnancy. STUDY DESIGN: Cross-sectional descriptive study. MATERIAL AND METHOD: The 255 singleton pregnant women < 20 weeks of gestation were enrolled. They were asked to complete a self-administered questionnaire which included Thai GHQ-30 (mental health problem screening tool) and frequent psychosocial stressor forms. The prevalence and factors associated with mental health problem were evaluated. MAIN OUTCOME MEASUREMENT: The prevalence of mental health problem. RESULTS: The prevalence of mental health problem was 17.3%. Factors independently associated with mental health problem included worrying about health, stress of taking care of other family members and financial problem with adjusted OR 3.5 (95% CI 1.16, 10.74), 3.8 (95% CI 1.80, 7.89) and 3.2 (95% CI 1.34, 7.53) respectively. CONCLUSION: The prevalence of mental health problem was 17.3%. Screening of mental health problem should be included in antenatal care service especially in the risk group.

Serotonin syndrome with rhabdomyolysis: A case report and recommended prevention.

Serotonin syndrome is a severe but preventable adverse drug reaction. This syndrome is rare and usually underrecognized. It is resulted from the excessive serotonin receptor stimulation, mostly by combination of serotonergic agents. The clinical triads are altered mental status, autonomic dysfunction and neuromuscular abnormalities. Occasionally, severe cases of serotonin syndrome are complicated by rhabdomyolysis and other potentially life-threatening conditions. In this report, we describe a 22-year-old man presenting with serotonin syndrome and rhabdomyolysis from serotonergic drug interaction. In addition, recommendation of preventive strategies is included.