ABSTRACT
Chronic Renal Disease is a Global Health Problem which has multiple clinical features which are problematic to the patient, reduces their life expectancy and changes their way of living. It is mainly comprised of hematuria, proteinuria and progressive loss of kidney function. If it reaches end-stage that means there is 90% loss of the kidney function. At times, it also gives rise to oral manifestations which are misdiagnosed and as a result go untreated. This review article deals with the oral manifestations of Chronic Renal Disease so that proper awareness of this problem can be met among Dentists as well.
ABSTRACT
Mastoid operations have been in practice for over four centuries for suppurative conditions of the ear. Intact canal wall mastoidectomy has the advantage of rapid wound healing and also avoids frequent cleaning of the cavity. With canal wall down mastoidectomy there is excellent exposure for disease eradication and post-operative monitoring but is associated with significant cavity problems. In order to overcome the problems associated with canal wall down procedure while retaining its advantages, the concept of mastoid cavity obliteration was introduced. We wanted to study the outcomes of mastoid cavity obliteration and compare the outcomes of mastoid cavity obliteration with autologous cartilage as obliterating material for mastoid obliteration. METHODSA prospective, experimental, randomized study has been conducted over a period of 18 months among patients presenting with active squamosal variety of Chronic Otitis Media wherein 15 cases were allotted to each group which subsequently underwent canal wall down mastoidectomy followed by obliteration with autologous cartilage. RESULTSThe mean age of the individuals in group A is 25.47 years with a standard deviation of 8.89 years; in group B (obliteration with cartilage) it is 26.33 years with a standard deviation of 11.73 years. In group A, the mean duration required for complete epithelialization is 10.8 weeks while in group B, the average time taken for complete epithelialization is 5.07 weeks. All cases had their graft intact at the end of 12 weeks. Debris was present in group A for a mean duration of 9.47 weeks whereas in group B it is seen for a mean duration of 2.8 weeks. Patients from group A complained of discharge from their ears for a mean duration of 7.47 weeks. In group B the same symptom persisted over 2.8 weeks.
ABSTRACT
Hysterectomy for fibroids is one of the commonest gynaecological surgeries in India. To reduce the morbidity and mortality associated with the surgery a number of medical treatments have been tried. Mifepristone is one of them and is being used in the recent decade as a more or less effective option in the treatment of myoma. This study was undertaken to evaluate the efficacy and safety of low dose mifepristone in medical management of uterine myomas. Women with symptomatic myomas or myoma of more than 5cm were included in this study. They were given oral mifepristone 25mg per day for 3 months. Patients were followed at 1, 3 and 6 months. The prospective clinical trial was conducted from august 2006 to august 2018 at my clinic. It was found that blood loss reduced significantly in 3 months therapy and the effect started from the first cycle onwards. Amenorrhoea developed in 90% - 95% patients which reverted later