ABSTRACT
Objective To investigate the effects of transcutaneous electrical acupoint stimulation (TEAS) and electro-acupuncture (EA) combined with local anesthesia on cerebral blood flow (CBF) and Brain function in CAS patients.Methods Eighty cases of CAS were randomly as signed into EA group (group A),TEAS group (group T) and sham group (group C).Patients in group A received EA at acupoints of Shuigou (GV26) and Baihui (GV20),Hegu (L14) and Waiguan (TE5) at the same side of the stenting before 30 min of operation.Patients in group T received TEAS at the same acupoints through self-adhesive skin electrodes.In group T and group A,stimulations were continued until the end of the operation.The patients in group C did not received EA or TEAS.Blood pressure (BP) and heart rate (HR) were maintained at + 10％-20％ of baseline.Preoperative and postoperative average Vm,PI,RI of middle cerebral artery were measured.The occurrence of hyperperfusion and preoperative and postoperative scores at 1 week,1 month,3 months National Institute of Health Stroke Scale and Global Assessment Scale were recorded.Results The Vm of groups A and T was significantly less than group C (P＜0.05).The incidence of hyperperfusion of groups A and T were 3.7％,0％ and 25.0％ respectively (P＜0.05).NIHSS score of group A and group T were lower than those of group C during postoperative 1 week,1 month,3 month (P＜0.05),while the difference between groups A and T had no statistical significance.GES score of group A and group T during postoperative 1 week improved significantly than that of group C (P＜0.05).Conclusion Both TEAS and EA combined with local anesthesia in CAS operation could reduce the increase of postoperative cerebral blood flow and the incidence of postoperative hyperperfusion,and obviously improve brain function during postoperative 1 week.Both TEAS and EA combined with local anesthesia could be a worthwhile anesthesia method in CAS patients.