The Clinical Significance of Ischemic Preconditioning in Aged Patients with Acute Myocardial Infarction / 中国医师杂志

Objective To investigate the effects of ischemic preconditioning(IPC)on aged patients with acute myocardial infarction(AMI). Methods 124 cases of AMI during hospitalization were divided into two groups: ischemic precondition group(IPC, n =68)with angina 48 hours before AMI; no ischemic precondition group (NIPC, n =56) without angina. The clinical data of the two groups were compared. Results The infarction size was smaller in the group IPC than that in the group NIPC ( P

Comparison on Pharmacodynamics Effects between Different Extracts of Fructus Trichosanthis and Bulbus Allii Macrostemi / 中成药

Objective: To compare pharmacodynamics properties between the extracts of Fructus Trichosanthis and Bulbus allii(water extraction, WE; ethanol extraction, EE). Methods: To establish model of normobaric hypoxia in mice with isoprenaline; determinated the coronary blood flow of isolated guinea pig heart and rabbits platelet aggregation induced by ADP in vitro. Results: EE was more effective than WE on the prolongation of survival time of mice; EE and WE significantly increased coronary blood flow and inhibited platelet aggregation at the same dose. Conclusion: At the same dose, the effect of EE is superior to WE.