ABSTRACT
Objective: to detect the impact of acne vulgaris on quality of life and assess correlation between disease severity, complications and decreased life quality
Methods: this cross-sectional study of one-year duration involving acne patients of 18-30 years was carried out after institutional Ethics Committee clearance. After written informed consent, patients filled a proforma including demographic data, treatment and previous psychiatric history. Clinical grade of acne and severity of pigmentation and scarring were noted. Acne severity was classified as mild, moderate or severe and DLQI was noted. Statistical analysis was performed with the Statistical Package for the Social Sciences [SPSS version 15.0], Chi-square test and Pearson's correlation coefficient
Results: overall mean DLQI was 7.84 [females 8.02, males 7.82] showing no significant difference between the genders. There was no association seen between DLQI scores severity and complications like pigmentation [p=0.198] and scarring [p=0.095]. There was significant association between severity of acne grades and DLQI scores [p=0.014]
Limitation: the study population was restricted to patients visiting our outpatient department. Only DLQI questionnaire was used for evaluation, which could detect psychosocial problems, but not depression or anxiety without clinical assessment
Conclusion: our study confirms a negative impact of acne on quality of life substantiating a holistic approach treating physique and psyche for well-being of the person
ABSTRACT
Urticaria pigmentosa is a fairly indolent form of cutaneous mastocytosis, which is more prevalent in infants than in adults. Adult onset disease is usually supposed to be associated with systemic disease and has a propensity for polycythemia vera and leukaemia in a certain percentage, though regression has been reported in as many as 19% cases. A useful clue to diagnose indolent forms from malignant forms is that invariably there is thrombocytopenia with leukocytosis in malignant forms. We report an adult female with typical lesions of urticaria pigmentosa, proven by skin biopsy, who showed a good response to H1 and H2 receptor blockage treatment
Subject(s)
Humans , Female , Urticaria Pigmentosa/pathology , Urticaria Pigmentosa/drug therapy , Histamine H1 Antagonists , Histamine H2 Antagonists , Adult , Mastocytosis, Cutaneous , Skin/pathologyABSTRACT
Erythromycin is a macrolide antibiotic active against many gram-positive infections and few gram-negative bacteria, as well as mycoplasmas, spirochetes, chlamydiae and rickettsiae. Dermatological reactions appear to be rare with erythromycin and mainly include maculopapular rashes, pruritus, urticaria, and angioedema, Reports of morbiliform rashes due to erythromycin are rare. We report a case of morbiliform reaction due to erythromycin in a patient suffering from herpes zoster with established causality, severity and preventability assessments. Upon development of the adverse drug reaction, we stopped the drug and managed the patient with systemic corticosteroids
ABSTRACT
Dermatological non disease, popularly known as body dysmorphic disorder is encountered among 9-15%of patients visiting a dermatology clinic. It in significant emotional distress and can be associated with other psychiatric disorders. Unfortunately the diagnosis is often missed. Patients insist on undergoing cosmetological procedures but are invariably dissatisfied with the results. This leads to litigations and even physical assaults, hence it is worthwhile for all dermatologists to be well aware of this entity
Subject(s)
Humans , Mental Disorders , Stress, Psychological , Prevalence , Delusions , Hypochondriasis , Shared Paranoid Disorder , Koro , DermatologyABSTRACT
Dapsone is a sulfone antimicrobial and is used widely as an antileprotic medication. The commonly encountered cutaneous adverse drug reactions [ADR] due to dapsone are exfoliative dermatitis, toxic 'erythema, erythema multiforme, morbilliform and scarlatiniform eruptions, urticaria, erythema nodusum and toxic epidermal necrolysis [TEN]. We hereby report a case of toxic epidermal necrolysis caused due to dapsone. The causality, severity and preventability assessments were carried out. The patient was treated with systemic hydrocortisone, antibiotics and other symptomatic drugs. The reaction was severe and the patient expired on the second day of hospital admission in spite of the treatment. Since TEN is a life threatening cutaneous ADR and dapsone is a commonly used drug, this reaction needs monitoring