ABSTRACT
Murakkab drugs of Unani medicine have remained an important aspect of disease treatment since antiquity. Physicians prepared different formulations for various diseases. The formulations thus preparedhave always been of two categories. One category of Murakkab drugs was those which were formulatedempirically and remained in use without conceptual framework behind these formulations. These formulations were categorized as Mujarrab (tested) formulations. The other category of formulations wasprepared in consideration with theoretical framework of Mizaj (temperament) and Usoole ilaj (treatmentstrategy) and then tested by physicians. This category forms a large chunk of formulations in the formulary sections of the literature of Unani medicine. Present paper explores various approaches forformulating Murakkab drugs of the second category keeping in view the actions of the ingredients of thedrug formulation, and treatment strategy of the disease for which the formulation was prepared. Itelucidates the approaches of formulating compound drug formulations with the logic of includingvarious individual ingredients. The study exemplifies two compound formulations to illustrate the approaches used to formulate compound formulations of Unani medicine.© 2017 Transdisciplinary University, Bangalore and World Ayurveda Foundation. Publishing Services byElsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).