Concurrent intramedullary spinal cord and intracranial tuberculomas

Tubeculosis commonly involves the nervous system, but involvement of spinal cord in the form of intramedullary tuberculoma is rare and concurrent occurrence of cranial and intramedullary tuberculomas is extremely rare. We report a case of concurrent occurrence of intramedullary tuberculoma with multiple intracranial tuberculomas in a young girl from lslamabad, who presented with one month history of paraplegia and with a sensory level at TB. MRI spine showed a well circumscribed lesion opposite T6, which was diagnosed as intramedullary tuberculoma. On cranial imaging, she was found to have multiple round contrast enhancing lesions which were diagnosed as intracranial tuberculomas based on their typical MRI findings. She had complete recovery with conventional treatment of ATT and steroids, without any surgical intervention. The follow-up MRI of patient showed disappearance and complete resolution of most of the lesions

Eperisone compared to Physiotherapy on muscular tone of stroke patiehts: a prospective randomized open study

To compare the effects of Eperisone, a muscle relaxant and physiotherapy on the muscular tone after stroke. Twenty six [26] patients were included from age 15 to 75 years in an open prospective randomized study of threeweeks duration and were treated with either Eperisone [n=13] or were advised to undergo formal physiotherapy [n=13] at the department of physiotherapy PIMS. The end point was observed in the form of change in the grade of tone. Safety and tolerability was assessed on the basis of adverse events. Eperisone was found to be comparable to physiotherapy in reducing the spasticity in patients after stroke and improved the grade of tone from 3-2 [n=2], 4-3 [n=2], 2-1[n=2]. The safety analysis showed persistent vomiting [n=1], fatigue [n=1], headache and dry mouth [n=2], epigastric pain [n=1] and slight changes in blood pressure under Eperisone which was generally well tolerated by the patients. Eperisone was found to be comparable to physiotherapy in its effects to improve spasticity in patients after stroke [p>0.05] [JPMA 55:202;2005]