ABSTRACT
We present a case of cervical cancer treated by concurrent chemoradiation. In radiation therapy part, the combination of the whole pelvic helical tomotherapy plus image-guided brachytherapy with megavoltage computed tomography of helical tomotherapy was performed. We propose this therapeutic approach could be considered in a curative setting in some problematic situation as our institution.
Subject(s)
Brachytherapy , Radiotherapy, Intensity-Modulated , Uterine Cervical NeoplasmsABSTRACT
We present a case of cervical cancer treated by concurrent chemoradiation. In radiation therapy part, the combination of the whole pelvic helical tomotherapy plus image-guided brachytherapy with megavoltage computed tomography of helical tomotherapy was performed. We propose this therapeutic approach could be considered in a curative setting in some problematic situation as our institution.
Subject(s)
Brachytherapy , Radiotherapy, Intensity-Modulated , Uterine Cervical NeoplasmsABSTRACT
PURPOSE: To evaluate association between equivalent dose in 2 Gy (EQD2) to rectal point dose and gastrointestinal toxicity from whole pelvic radiotherapy (WPRT) and intracavitary brachytherapy (ICBT) in cervical cancer patients who were evaluated by rectosigmoidoscopy in Faculty of Medicine, Chiang Mai University. MATERIALS AND METHODS: Retrospective study was designed for the patients with locally advanced cervical cancer, treated by radical radiotherapy from 2004 to 2009 and were evaluated by rectosigmoidoscopy. The cumulative doses of WPRT and ICBT to the maximally rectal point were calculated to the EQD2 and evaluated the association of toxicities. RESULTS: Thirty-nine patients were evaluated for late rectal toxicity. The mean cumulative dose in term of EQD2 to rectum was 64.2 Gy. Grade 1 toxicities were the most common findings. According to endoscopic exam, the most common toxicities were congested mucosa (36 patients) and telangiectasia (32 patients). In evaluation between rectal dose in EQD2 and toxicities, no association of cumulative rectal dose to rectal toxicity, except the association of cumulative rectal dose in EQD2 >65 Gy to late effects of normal tissue (LENT-SOMA) scale > or = grade 2 (p = 0.022; odds ratio, 5.312; 95% confidence interval, 1.269-22.244). CONCLUSION: The cumulative rectal dose in EQD2 >65 Gy have association with > or = grade 2 LENT-SOMA scale.
Subject(s)
Humans , Brachytherapy , Estrogens, Conjugated (USP) , Mucous Membrane , Odds Ratio , Radiotherapy , Rectum , Retrospective Studies , Telangiectasis , Uterine Cervical NeoplasmsABSTRACT
Objectives Materials and methods fi ve had boost treatment after external irradiation. Aftertreatment was completed, the patients were appointed to attend a follow-up program toevaluate results and toxicities.Results fi stula, due to tumour progression.Conclusions fi t and gain of the patients. Chiang Mai MedicalJournal 2009;48(4):151-157.Interstitial brachytherapy can be used as an option to irradiate patients andboost treatment. However re-irradiation with brachytherapy should be critically evaluatedfor toxicities and local control for the beneAt the median follow up of 5 months, Three patients (23%) yielded good localcontrol. One patient developed vesico-vaginalFrom January 2007 to December 2008, thirteen patients withgynaecological cancers were treated by interstitial brachytherapy. Eight patients wererecurrent after irradiation andTo report the results of interstitial brachytherapy (ISBT) in gynaecologicalcancers.