Psiconeuroinmunoendocrinología en enfermedades autoinmunes (LES) / Psychoneuroimmunoendocrinology in autoimmune disease

When we first defined in 1990 the term Psychoneuroimmunoendocrinology considering the interrelation of both the immune and the endocrine systems, the neurotransmitter receptors and the endocrine systems, the neurotransmitter receptors and the main findings in the field of psychology, an increasing ethusiasm was originated following the expression of these concepts, and rapidly clinical physicians and immunotherapeutists hypothesized the possibility of the existence of a molecular basis in the observations produced daily during their assistance. The authors describe these immuno-neuroendocrinal interactions, with special reference to psychoneuroimmuno-endocrinology in the systemic lulpus erythmatosus