ABSTRACT
Objective To investigate the secondary prevention in acute coronary syndrome patients receiving percutaneous coronary intervention (PCI) during hospitalization and after discharge from Changhai Hospital. Methods The clinical data of patients with acute coronary syndrome undergoing PCI in Changhai Hospital from Jan 1st. 2009 to Dec 31st. 2011 were collected. Thestatus of secondary prevention and drug therapies was analyzed at 1 month, six months and 1 year after discharge. Results A total of 238 patients with acute coronary syndrome receiving PCI were included in the present study. Smoking patients were forced to quit during hospitalization; the application rates of aspirin, angiotensin-converting enzyme inhibitors (ACEI)/angiotensin II receptorblockers (ARB), β-blockers and statins among patients were 96. 6%, 73. 1%, 68.9% and 92.4%, respectively. At 1 month, 6 months and 1 year after discharge, the application rates of aspirin among the patients were 98. 3%, 95. 8% and94. 1%; of ACEI/ARB were 72. 3%, 69. 7% and63. 4%; of -blockers were 68. 1%, 62.2% and 52. 1%; and of statins were 91. 6%, 88. 7% and83. 6%, respectively. At 1 month, six months and 1 year after discharge, the non-smoking rates were 86. 4%,77. 9% and 78. 6% in male patients and 100%, 98. 8% and 98. 8% in female patients, respectively; the control rates of blood pressure were 93. 3%, 95. 4% and 94. 3% and those of blood glucose were 98. 3%, 96. 2% and undergoing PCI, but the situation gradually worsened after discharge; therefore efforts should be made to strengthen the follow-up and health education of the patients so as to reinforce secondary prevention for coronary heart disease.
ABSTRACT
<p><b>OBJECTIVE</b>To determine the allelic sequences and genetic polymorphism of six short tandem repeats (STRs) loci on Y chromosome, including DYS441, DYS442, DYS443, DYS444, DYS445 and DYS446 in Chinese Korean ethnic males from Yanbian region of Jilin province, China, and to construct a preliminary database.</p><p><b>METHODS</b>Allele frequencies of the six STR loci in 205 Chinese Korean ethnic individuals were analyzed by multiplex polymerase chain reaction (PCR) and polyacrylamide gel electrophoresis (PAGE).</p><p><b>RESULTS</b>Respectively, 8, 7, 7, 5, 6 and 9 alleles were detected for each of the locus. Together they have formed 151 haplotypes, with a diversity of 0.9937.</p><p><b>CONCLUSION</b>The six STR loci included in this study were found to be highly polymorphic, and may provide useful markers for genetic analysis.</p>