ABSTRACT
OBJECTIVE To discuss the distribution of pathogens isolated from the hospitalized patients of lower respiratory infection in the department of respiratory medicine and their drug resistance to help reasonably utilize the antibiotics.METHODS By the retrospective methods,we analyzed the pathogens isolated from the sputa of the hospitalized patients with lower respiratory tract infection in the department of respiratory medicine from 2002 to 2006 and their drug resistance.RESULTS Gram-negative bacteria were 46.5-56%,Pseudomonas aeruginosa and Escherichia coli were 15.0% and 8.9%,respectively,the drug resistance ratio to imipenem,piperacillin/tazobactam and amikacin was 2.0-35.6%;Gram-positive bacteria were 23.1-36.3%,Staphylococcus aureus and coagulase negative Staphylococcus were 17.3% and 7.5%,respectively,only to vancomycin were without resistance.Fungi were 15.3-24.7%.CONCLUSIONS Gram-negative bacteria are the main ones in lower respiratory tract infection,Gram-positive bacteria have a rising tendency and fungi occupy a fixed ratio.The drug resistance increases constantly.So it is very important to utilize antibiotics reasonably and pay attention to supervising drug resistance.