Induced eye infection in rat with Staphylococcus aureus.

The pathogenicity of one Staphylococcus aureus strain HI/F-20 was assessed by infecting normal pathogen-free mice. The bacterium which caused death of mice then use to investigate ocular infection in rat. Eye infection was induced by injecting microorganism transcorneally and through catheterized common carotid artery respectively. Transcorneal infection resulted in reversible changes which were limited to the anterior chamber. These changes could be attributed to traumatization of the ocular tissues. The haematogenous infection made though the catheterized carotid artery resulted in an endophthalmitis with retinochoroidal oedema and hypereamia which were confirmed histologically.