ABSTRACT
BACKGROUND: Perioperative hypothermia is a common problem during both laparotomy and laparoscopic surgery. Hypothermia during laparoscopic surgery is related to the use of irrigation fluid and the large volume of CO2 for maintaining pneumoperitoneum. The aim of this study is to estimate whether the use of warm irrigation fluid can reduce the incidence of hypothermia and the decrease of body temperature. METHODS: Forty-two female patients undergoing elective laparoscopic surgery were randomly divided into 2 groups. Group 1 (n = 20) was given an ambient temperature irrigation fluid and group 2 (n = 22) a warm irrigation fluid. The core esophageal body temperatures of all the patients were measured every 10 minutes for 70 minutes. Body temperature 10 minutes after induction was a control value. The degree of body temperature decrease was measured, and the incidence of hypothermia was recorded. RESULTS: The incidences of hypothermia in group 2 were decreased significantly 60 and 70 minutes after induction, compared with those of group 1. The degree of body temperature decrease was revealed to be significantly different between the two groups starting 50 minutes after induction. CONCLUSIONS: The use of warm irrigation fluid during laparoscopic surgery can reduce the incidence of hypothermia and degree of body temperature decrease.
Subject(s)
Female , Humans , Body Temperature , Hypothermia , Incidence , Laparoscopy , Laparotomy , PneumoperitoneumABSTRACT
BACKGROUND: Perioperative hypothermia is a common problem during both laparotomy and laparoscopic surgery. Hypothermia during laparoscopic surgery is related to the use of irrigation fluid and the large volume of CO2 for maintaining pneumoperitoneum. The aim of this study is to estimate whether the use of warm irrigation fluid can reduce the incidence of hypothermia and the decrease of body temperature. METHODS: Forty-two female patients undergoing elective laparoscopic surgery were randomly divided into 2 groups. Group 1 (n = 20) was given an ambient temperature irrigation fluid and group 2 (n = 22) a warm irrigation fluid. The core esophageal body temperatures of all the patients were measured every 10 minutes for 70 minutes. Body temperature 10 minutes after induction was a control value. The degree of body temperature decrease was measured, and the incidence of hypothermia was recorded. RESULTS: The incidences of hypothermia in group 2 were decreased significantly 60 and 70 minutes after induction, compared with those of group 1. The degree of body temperature decrease was revealed to be significantly different between the two groups starting 50 minutes after induction. CONCLUSIONS: The use of warm irrigation fluid during laparoscopic surgery can reduce the incidence of hypothermia and degree of body temperature decrease.
Subject(s)
Female , Humans , Body Temperature , Hypothermia , Incidence , Laparoscopy , Laparotomy , PneumoperitoneumABSTRACT
BACKGROUND: Epidural pain control has been used extensively for postoperative pain management, but nausea, vomiting and pruritus associated with morphine and fentanyl administration remain intractable problems. The aim of this study is to find the optimal epidural droperidol dosage for reducing the side effects of epidural morphine and fentanyl. METHODS: 140 patients randomly sampled and undergoing vaginal total hysterectomy were divided into 7 groups. Groups I and IV, and groups II and V, and groups III and VI, received 5 mg, 3.75 mg, 2.5 mg of droperidol by 2-day infusion pump through the indwelling epidural catheter, respectively. Group IV, V, VI patients received 1.25 mg of bolus droperidol through the indwelling epidural catheter at the time of peritoneal closure. As group VII was the control group, these patients received only epidural analgesics (morphine 10 mg, fentanyl citrate 300 microgram and 0.05% bupivacaine 100 ml) by 2-day infusion pump. RESULTS: Droperidol significantly reduced the incidence and severity of postoperative nausea, vomiting and itching sensation compared with the control group but verbal rating scale (VRS) of sedation was increased with the dosage of droperidol. There was no significant difference in the intensity of analgesia between the there groups. CONCLUSIONS: An effective epidural droperidol dosage for reducing postoperative nausea, vomiting and pruritus due to epidural pain control is 2.5 mg by 2-day infusion pump.
Subject(s)
Humans , Analgesia , Analgesics , Bupivacaine , Catheters , Droperidol , Fentanyl , Hysterectomy , Incidence , Infusion Pumps , Morphine , Nausea , Pain Management , Pain, Postoperative , Postoperative Nausea and Vomiting , Pruritus , Sensation , VomitingABSTRACT
BACKGROUND: Epidural pain control has been used extensively for postoperative pain management, but nausea, vomiting and pruritus associated with morphine and fentanyl administration remain intractable problems. The aim of this study is to find the optimal epidural droperidol dosage for reducing the side effects of epidural morphine and fentanyl. METHODS: 140 patients randomly sampled and undergoing vaginal total hysterectomy were divided into 7 groups. Groups I and IV, and groups II and V, and groups III and VI, received 5 mg, 3.75 mg, 2.5 mg of droperidol by 2-day infusion pump through the indwelling epidural catheter, respectively. Group IV, V, VI patients received 1.25 mg of bolus droperidol through the indwelling epidural catheter at the time of peritoneal closure. As group VII was the control group, these patients received only epidural analgesics (morphine 10 mg, fentanyl citrate 300 microgram and 0.05% bupivacaine 100 ml) by 2-day infusion pump. RESULTS: Droperidol significantly reduced the incidence and severity of postoperative nausea, vomiting and itching sensation compared with the control group but verbal rating scale (VRS) of sedation was increased with the dosage of droperidol. There was no significant difference in the intensity of analgesia between the there groups. CONCLUSIONS: An effective epidural droperidol dosage for reducing postoperative nausea, vomiting and pruritus due to epidural pain control is 2.5 mg by 2-day infusion pump.
Subject(s)
Humans , Analgesia , Analgesics , Bupivacaine , Catheters , Droperidol , Fentanyl , Hysterectomy , Incidence , Infusion Pumps , Morphine , Nausea , Pain Management , Pain, Postoperative , Postoperative Nausea and Vomiting , Pruritus , Sensation , VomitingABSTRACT
Type F collagen is the major component of the basement membrane (BM) and is considered to act as a barrier during tumor invasion. In order to demonstrate the changes of type IV collagen in the BM. immunohistochemical methods were used in normal bladder and 27 cases of transitionral cell carcinoma (TCC) of the bladder for which clinical follow-up was available. Normal epithelial structures were urrounded by a generally intact BM type F collagen. In stage Ta lesion, type IV collagen was single layered but regular continuous linear fashion. In stage T1 or T2 lesion, they were partially disrupted in areas of invasion with irregular contour. In stage T3 lesion, type IV collagen was completely absent from BM. Above findings are very similar to our previous BM laminin study in bladder cancer. It supports the hypothesis that tumor cell conjugates with BM laminin and release the type IV collagenase which degrades the BM type IV collagen. In conclusion, it is suggested that both BM laminin and type IV collagen disappear in the area of invasion and the disappearance of BM type IV collagen in superficial disease may also provide early indication of invasive disease and careful monitoring ismandatory.
Subject(s)
Basement Membrane , Carcinoma, Transitional Cell , Collagen , Collagen Type IV , Collagenases , Follow-Up Studies , Laminin , Urinary Bladder Neoplasms , Urinary BladderABSTRACT
Mesothelioma is a neoplasm arising from the mesothelial cells lining the serous membrane such as pleura, peritoneum. and tunica vaginalis of testis. Primary malignant mesothelioma of tunica vaginalis is rare and there was no report in Korean literature yet. We report a case of a 43-year-old man with a painless palpable growing mass and histopathologically demonstrated to a malignant mesothelioma arising from the tunica vaginalis of testis.