ABSTRACT
Castleman's disease, or angiofollicular lymph node hyperplasia, is a rare disorder that involves the proliferation of lymphoid tissue. The disease entity is classified into three pathologic subtypes, namely, the hyaline vascular, plasma cell, and mixed types; however, clinically, they are classified as unicentric and multicentric types. The former is treated primarily by excision, whereas systemic therapies have been used to treat the latter form, because of its more aggressive pattern. We report a case of a 17-year-old woman who underwent an excisional biopsy of one of the multiple affected cervical lymph nodes. A subsequent histopathologic examination revealed hyaline vascular Castleman's disease. One month later, the disease spontaneously regressed and no recurrence was observed over a 12-month period following the excisional biopsy.
Subject(s)
Adolescent , Female , Humans , Biopsy , Castleman Disease , Hyalin , Lymph Nodes , Lymphoid Tissue , Lymphoproliferative Disorders , Neck , Plasma Cells , Recurrence , Remission, SpontaneousABSTRACT
BACKGROUND AND OBJECTIVES: Olfaction is a critical function of our body that allows one to avoid potential dangers in daily living. Although there are numerous subjective and objective tests evaluating the olfactory function, there exist no studies assessing correlations among such tests for various causes of olfactory dysfunction, especially in Korea. SUBJECTS AND METHOD: We collected the olfactory functional test results of 473 subjects who visited our outpatient clinic. We categorized these patients into 5 groups: head trauma, post-upper respiratory infection, chronic sinonasal disease, toxic exposure, and idiopathic. All patients were examined using the Butanol Threshold Test (BTT) and Cross Cultural Smell Identification Test (CC-SIT). The patients' subjective symptoms were recorded using the Visual Analog Scale (VAS). RESULTS: The three tests showed significant correlations in different pairs (CC-SIT and BTT; r=0.512, p<0.001, BTT and VAS; r=0.558, p<0.001 and VAS & CC-SIT; r=0.567, p<0.001). Correlation results were lower in patients with olfactory disorders caused by an upper respiratory infection and head trauma than in those with olfactory disorders caused by sinonasal diseases. CONCLUSION: The results from all three tests showed significant correlations with one another. CC-SIT and VAS score seem to represent the olfactory loss caused by sensorineural dysfunction better than BTT.
Subject(s)
Humans , Ambulatory Care Facilities , Craniocerebral Trauma , Olfaction Disorders , SmellABSTRACT
Paget's disease is a localized bone disorder that affects widespread areas of skeleton characterized by increased bone remodeling. It is a chronic, progressive disease of unknown etiology. The pathologic process is initiated by hyperactive osteoclastic bone resorption followed by a compensatory increase in the osteoblastic new bone formation. New pagetic bones are disorganized and more susceptible to deformities and fractures. Paget's disease can affect one or multiple bones in the systemic skeleton, including the temporal bone. We experienced a case of chronic otitis media combined with an external auditory canal stenosis due to Paget's disease of the temporal bone. We report clinicopathologic features of this rare case.
Subject(s)
Bone Remodeling , Bone Resorption , Congenital Abnormalities , Constriction, Pathologic , Ear Canal , Osteoblasts , Osteoclasts , Osteogenesis , Otitis Media , Skeleton , Temporal BoneABSTRACT
Osteomyelitis caused by maxillary sinusitis is clinically rare. We report a case of a 43-year-old woman who presented with an oroantral fistula on the hard palate, originating from osteomyelitis complicated by maxillary sinusitis. To our knowledge, oroantral fistula on the hard palate caused by chronic rhinosinusitis is rare. Physical, radiological, and cytological findings revealed the clues suggesting osteomyelitis. We performed endoscopic sinus surgery for the sinus lesion and the fistula healed spontaneously after the procedure.
Subject(s)
Adult , Female , Humans , Fistula , Maxillary Sinus , Maxillary Sinusitis , Oroantral Fistula , Osteomyelitis , Palate, HardABSTRACT
Iatrogenic epidermoid cyst of the retroauricular area after ear surgery is extremely unusual. Epidermoid cyst is an intradermal or subcutaneous sac-like structure which is lined with well differentiated stratified squamous epithelium containing keratohyalin granules. These cysts are thought to arise as a result of implantation of epidermal cells into the deeper dermal elements by trauma or previous surgery. We report a 42-year-old female with retroauricular epidermoid cyst invading into the temporal bone who underwent tympanoplasty 15 years ago. The lesion was surgically excised, histopathologic examination revealed an epidermoid cyst. Therefore we report the case along with review of literature.