ABSTRACT
BACKGROUND/AIMS: Newer operative link for gastritis assessment (OLGA) system tried to stage gastritis in view of gastric cancer (GC) risk and endoscopic atrophic border (EAB) was well correlated with OLGA. We described the gastritis on the base of EAB during endoscopic sessions and classified them into high or low stage gastritis as suggested by Quach et al. and analyzed them. MATERIALS AND METHODS: A total of 158 subjects who visit our health promotion center were graded on the base of EAB by conventional endoscopy and reallocated according to ages. Linear-by-linear association was performed to identify the differences of gastritis among age-groups. RESULTS: In our study 31% of patients had atrophic gastritis (AG) over AG closed type 3~open type 1 compatible with OLGA stages III/IV (high stage gastritis). High and low stage gastritis showed significantly different distribution at each age group. The proportion of endoscopically diagnosed high stage gastritis increased in proportion to age. Contrast to Quach et al. our study showed prevalence of high stage gastritis under 40s, even in 20s or 30s (P=0.002). CONCLUSIONS: OLGA based EAB is easy and useful in GC risk stratification. In our study unlike the previous study of Quach et al., high stage gastritis was found in younger age groups. We should and could make an effort to prevent GC in even younger age groups with the aid of EAB. Additionally we could get organized and communicable stratified data about GC risk.
Subject(s)
Humans , Atrophy , Endoscopy , Gastritis , Gastritis, Atrophic , Health Promotion , Prevalence , Stomach NeoplasmsABSTRACT
BACKGROUND/AIMS: Newer operative link for gastritis assessment (OLGA) system tried to stage gastritis in view of gastric cancer (GC) risk and endoscopic atrophic border (EAB) was well correlated with OLGA. We described the gastritis on the base of EAB during endoscopic sessions and classified them into high or low stage gastritis as suggested by Quach et al. and analyzed them. MATERIALS AND METHODS: A total of 158 subjects who visit our health promotion center were graded on the base of EAB by conventional endoscopy and reallocated according to ages. Linear-by-linear association was performed to identify the differences of gastritis among age-groups. RESULTS: In our study 31% of patients had atrophic gastritis (AG) over AG closed type 3~open type 1 compatible with OLGA stages III/IV (high stage gastritis). High and low stage gastritis showed significantly different distribution at each age group. The proportion of endoscopically diagnosed high stage gastritis increased in proportion to age. Contrast to Quach et al. our study showed prevalence of high stage gastritis under 40s, even in 20s or 30s (P=0.002). CONCLUSIONS: OLGA based EAB is easy and useful in GC risk stratification. In our study unlike the previous study of Quach et al., high stage gastritis was found in younger age groups. We should and could make an effort to prevent GC in even younger age groups with the aid of EAB. Additionally we could get organized and communicable stratified data about GC risk.
Subject(s)
Humans , Atrophy , Endoscopy , Gastritis , Gastritis, Atrophic , Health Promotion , Prevalence , Stomach NeoplasmsABSTRACT
Skull base osteomyelitis (SBO) is difficult to diagnose when a patient presents with multiple cranial nerve palsies but no obvious infectious focus. There is no report about SBO with septic pulmonary embolism. A 51-yr-old man presented to our hospital with headache, hoarseness, dysphagia, frequent choking, fever, cough, and sputum production. He was diagnosed of having masked mastoiditis complicated by SBO with multiple cranial nerve palsies, sigmoid sinus thrombosis, and septic pulmonary embolism. We successfully treated him with antibiotics and anticoagulants alone, with no surgical intervention. His neurologic deficits were completely recovered. Decrease of pulmonary nodules and thrombus in the sinus was evident on the follow-up imaging one month later. In selected cases of intracranial complications of SBO and septic pulmonary embolism, secondary to mastoiditis with early response to antibiotic therapy, conservative treatment may be considered and surgical intervention may be withheld.
Subject(s)
Humans , Male , Middle Aged , Anti-Bacterial Agents/therapeutic use , Anticoagulants/therapeutic use , C-Reactive Protein/analysis , Cranial Nerve Diseases/complications , Diagnosis, Differential , Enterobacter aerogenes/isolation & purification , Enterobacteriaceae Infections/diagnosis , Lung/pathology , Magnetic Resonance Imaging , Mastoiditis/complications , Osteomyelitis/complications , Pulmonary Embolism/complications , Sinus Thrombosis, Intracranial/complications , Skull Base , Sputum/microbiology , Tomography, X-Ray ComputedABSTRACT
Hemophagocytic lymphohistiocytosis (HLH) is a rare disease with a high mortality rate. It is associated with a variety of bacterial, viral, fungal, and parasitic infections. In the literature, there are several cases of HLH associated with scrub typhus in adults, all of which were successfully treated with antibiotic therapy for scrub typhus. This report describes a case of HLH accompanied by scrub typhus in an 81-year-old woman, in whom the disease progressed despite doxycyclin therapy. The patient refused to receive immunosuppressive chemotherapy for HLH and died 5 weeks after admission due to multi-organ failure. To our knowledge, this is the first case of death due to scrub typhus-associated HLH in an adult.
Subject(s)
Adult , Aged, 80 and over , Female , Humans , Lymphohistiocytosis, Hemophagocytic , Rare Diseases , Scrub TyphusABSTRACT
Follicular dendritic cells (FDC) are non-lymphoid, non-phagocytic accessory cells of the immune system and these cells are essential for antigen presentation and regulation of the reactions in germinal centers. Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm that shows a low-to-intermediate malignant potential. The most commonly involved sites are the lymph nodes, but FDCS may also occur at a variety of extranodal sites, including the oral cavity, tonsils, gastrointestinal tract and liver. We describe here a 79-year-old woman who had FDCS with extensive lymph node involvement, dry cough, and an itching sensation. The patient improved after systemic chemotherapy.
Subject(s)
Aged , Female , Humans , Antigen Presentation , Cough , Dendritic Cell Sarcoma, Follicular , Dendritic Cells , Dendritic Cells, Follicular , Gastrointestinal Tract , Germinal Center , Immune System , Liver , Lymph Nodes , Mouth , Palatine Tonsil , Pruritus , SensationABSTRACT
Cholethorax (bilious pleural effusion) is an extravasation of bile into the thoracic cavity via a pleurobiliary fistula (and also a bronchobiliary fistula). It is an extremely rare complication of thoraco-abdominal injuries. It can be caused by congenital anomaly and also by hepatobiliary trauma, severe infection or iatrogenic procedures. The definitive diagnosis is made with aspiration of bilious fluid from the pleural space during thoracentesis, by finding a fistulous tract during endoscopic retrograde cholangiopancreatography (ERCP) or cholagioscopy, or with finding an abnormal pleural accumulation of radioisotope during hepatobiliary nuclear imaging. Its symptoms include coughing, fever, dyspnea and pleuritc chest pain. Herein we report on a case of cholethorax following performance of percutaneous transhepatic cholangioscopy (PTCS) to remove incidentally discovered common bile duct (CBD) stones.
Subject(s)
Bile , Biliary Fistula , Chest Pain , Cholangiography , Cholangiopancreatography, Endoscopic Retrograde , Common Bile Duct , Cough , Dyspnea , Fever , Fistula , Pleural Effusion , Technetium Tc 99m Diethyl-iminodiacetic Acid , Thoracic CavityABSTRACT
No abstract available.