ABSTRACT
Aim of The Study: Evaluation of the activity of the expression of Ecballium elaterium fruit on the harm of pre hepatic cell level in heamolytic jaundice induced by phenylhydrazine. This activity was studied on five groups of Wister rats as following:1-normal group, 2-The group which given phenylhydrazine, subcutaneous, 3-The group which given Ecballium elaterium fruit juice intra nasal after the injury inducing, 4-The group which given a single dose of Ecballium elaterium fruit juice intravenous, 5-The group which given a single dose of reference drug phenobarbital Intra peritoneal
Results: The results of total direct and indirect bilirubin measurement showed a distinct in the sickness group comparing with normal group. The treated group by fruit juice showed significant improvement by inducing it intra venous and intra nasal ways, but the values of total; direct and indirect bilirubin in treated group by intra venous was closer to the normal values
Conclusion: This study showed that Ecballium elaterium fruit juice has activity in the treatment of heamolytic jaundice, by reducing the total; direct and indirect bilirubin values in intra venous and intra nasal, and the activity was more significant after inducing intra venous way