ABSTRACT
Disseminated blastomycosis is rare in India, particularly in the pediatric population. We discuss the clinical picture, progress and outcome of disseminated blastomycosis in a 4-year-old child. We also present a brief review of the literature focussing on the scenario of blastomycosis in India.
Subject(s)
Amphotericin B/therapeutic use , Anti-Inflammatory Agents/therapeutic use , Antifungal Agents/therapeutic use , Blastomycosis/drug therapy , Blastomycosis/pathology , Child, Preschool , Dexamethasone/therapeutic use , Fatal Outcome , Humans , India , Male , Rural HealthABSTRACT
Xeroderma pigmentosum [XP] is characterized by hypersensitivity to sunlight, ocular involvement, and progressive neurological complications. These manifestations are due to a cellular hypersensitivity to ultraviolet radiation leading to a defect in repair of DNA by the process of nucleotide excision repair. Basal cell carcinoma which is rare in children can occur with XP. Though the XP induced changes are predominately dermatologic, pose several challenges in anaesthetic management. Hence, we are reporting a 9-year-old child with XP scheduled for excision of basal cell carcinoma under general anaesthesia