ABSTRACT
Deep penetrating nevus (DPN) is a variant of melanocytic nevus which goes unrecognized due to its relative rarity and may be misinterpreted as malignant melanoma. It commonly presents in young adults as a dark pigmented lesion on the face, neck, or shoulder. A 60-year-old lady presented with a mole over the left arm of 8 years duration. A biopsy of the lesion was performed under the clinical impression of a compound nevus with suspicion of malignancy. Based on the histologic features, a diagnosis of DPN was put forward.
Subject(s)
Animals , Arm/pathology , Biopsy , Female , Histocytochemistry , Humans , Microscopy , Middle Aged , Nevus, Pigmented/diagnosis , Nevus, Pigmented/pathologySubject(s)
Adult , Cytomegalovirus Infections/complications , Cytomegalovirus Infections/pathology , Esophageal Diseases/diagnosis , Esophageal Diseases/pathology , Esophagoscopy , Esophagus/pathology , HIV Infections/complications , HIV Infections/diagnosis , Herpes Simplex/complications , Herpes Simplex/diagnosis , Histocytochemistry , Humans , Male , Microscopy , Ulcer/diagnosis , Ulcer/pathologyABSTRACT
Well differentiated villoglandular adenocarcinoma of uterine cervix is a rare tumour which usually occurs in young women. It is considered to be an indolent tumour with favorable prognosis and most of them were treated by conservative procedures. We report a 35 year old lady who came with complaints of 3 months amenorrhoea and an episode of spontaneous bleeding. Urine pregnancy test was negative. Physical examination revealed a cervical polyp. Histopathological findings were consistent with villoglandular papillary adenocarcinoma associated with high grade cervical intraepithelial neoplasia (CIN-3). Left parametrial and left ureteral involvement, proved by biopsy, causing left hydroureteronephrosis was detected. The patient was thus found to be in an advanced stage, stage- III b (FIGO). The patient is currently undergoing radiotherapy. A review of literature showed that only occasional cases showing disease spread have been reported, suggesting caution in the management and regular follow up of the patient.