ABSTRACT
Circadian variations in conjunction with sleep-related heart rhythm changes and sleep disordered breathing (SDB) are contributing risk factors for stroke. Strong scientific evidence now exists indicating that SDB contributes to systemic hypertension, a prominent risk factor for stroke, and compelling circumstantial evidence is present suggesting that SDB raises the risk for development of stroke through other circulatory mechanisms as well. Preliminary evidence indicates that post-stroke patients have a higher prevalence of SDB, which is likely to compromise their rehabilitation outcomes. Since SDB is modifiable with the application of CPAP and other treatment modalities, there is practical value in investigating patients at risk of stroke or post stroke for presence of SDB. Successful application of CPAP or BiPAP therapy may improve the outcome in both instances.