ABSTRACT
Objective To investigate the incidence of nutritional risk in infants with lower respiratory tract infection, and to compare the effects of different nutritional risks on clinical outcomes, and to provide evi-dence for clinical nutritional management of infantile lower respiratory tract infection. Methods Infants and young children with lower respiratory tract infection who were hospitalized in our hospital from January 2013 to March 2016 were selected as subjects. Nutritional risk screening was performed using the Nutritional Status and Growth Risk Screening Tool ( STRONGkids) . Results A total of 957 infants with lower respiratory tract infec-tions were included in the study. The incidence of high nutrition risk and low and medium nutritional risk were 17. 6％ and 82. 4％, respectively. The clinical cure rate was 68. 5％ and 71. 4％ respectively. The children with pneumonia and bronchitis had high nutritional risk. The incidence rates were 20. 60％ and 4. 87％, respectively, and the difference was statistically significant (χ2=25. 52, P=0. 000) . Time-effect single factor analysis ( Kaplan-Meier method):The hospitalization time for infants with low nutritional risk and high nutri-tional risk was 9. 3 ( 0. 3) d and 13. 3 ( 1. 0) d, respectively. The difference between the two groups was sta-tistically significant. (χ2=28. 33, P=0. 000) , the total hospitalization expenses were 5653. 5 ( 224. 8) yuan and 10079. 5 ( 1755. 8) yuan respectively. The difference between the two groups was statistically significant (χ2=4. 47, P=0. 034) . Multivariate COX regression analysis:High nutritional risk was a risk factor for hospi-talization of hospitalized infants with lower respiratory tract infection ( RR=1. 57, P=0. 024 ) . Conclusion There is a high incidence of high nutritional risk in infants with lower respiratory tract infection. Compared with children with low and moderate nutritional risk, the hospitalization time is longer, the hospitalization cost is in-creased, and the clinical cure rate is lower, which is the risk of clinical outcome. factor. Therefore, it is neces-sary to conduct nutrition risk screening for infants with lower respiratory tract infections, and provide a theoreti-cal basis for clinical nutrition evaluation and nutritional intervention.
ABSTRACT
OBJECTIVE: To investigate the etiology of infant cholestasis,and to evaluate the commonly clinical diagnostic methods in diagnosing infant biliary atresia(BA). METHODS: A total of 142 hospitalized children with infant cholestasis in the pediatric ward of our hospital from January 1,2012 to November 30,2016 were included. RESULTS: Totally 99 cases(69.7%)were comfirmed,and the most common causes were BA,cytomegalovirus infection and citrin protein deficiency.Totally 37 cases(26.1%)were diagnosed as idiopathic infant hepatitis and 6 cases(4.2%)were undiagnosed. Compared with no-BA group,acholie stools predominated in BA group,and the serum γ-GT in BA were significantly higher. Abdominal ultrasonography showed that 81.2% were cholecyst undiscovered or small in size in BA. Hepatobiliary scintigraphy(HBS)showed that 95.0% had no image of gallbladder or radioactive concentration in bowel and 5.0% had delayed image or radioactive conceatration in BA. The difference between the two group;was statistical(P<0.01). The sensitivity,specificity,and accuracy of acholic stools to diagnose BAwere 91.3%,92.9%,and 92.2%,γ-GT≥300 U/Lwere 65.2%,91.8%,83.3%,abdominal ultrasonography were 68.8%,90.8%,84.9%,HBS were 95%,50%,68.0%,respectively. CONCLUSION: The common causes of infant cholestasis in BA,idiopathic hepatitis,cytomegalovirus infection,and Citrin protein deficiency. In the infant cholestasis with acholic stools,infracostal liver≥3 cm,serum γ-GT≥300 U/L,cholecyst undiscovered or small in size in abdominal ultrasonography,HBS undiscovered or delayed image of gallbladder or radioactive concentration in bowel,the BA should be suspected.