Comparison of EffectiveNESS between Recombinant Follicle Stimulating Hormone and Human Menopausal Gonadotrophin Administration in those with Diminished Ovarian Reserve.

The study was carried out to compare the effectiveness of recombinant follicle stimulating hormone (recombinant FSH) and human menopausal gonadotrophin (HMG) in those with diminished ovarian reserve. A total of 106 ovarian stimulation cycles from 88 poor responders were included in this study. Either recombinant FHS or HMG was administered in order to stimulate the ovary for each cycle. The pregnancy rate of the recombinant FSH group (22.5%) was higher than that of the HMG group (9.1%). The cancellation rate of the recombinant FSH group (10.0%) was lower than that of the HMG group (19.7%). In in vitro fertilisation-embryo transfer (IVF-ET) cycles, the fertilisation rate of the recombinant FSH group (62.8%) was higher than that of the HMG group (51.8%). The pregnancy rate and the implantation rate of the recombinant FSH group (23.0 and 9.1%, respectively) were higher than those of the HMG group (13.6 and 5.9%, respectively). Although this did not achieve statistical significance, only the recombinant FSH group achieved pregnancies using gamete intrafallopian transfer (GIFT). In conclusion, recombinant FSH is probably more effective than HMG in improving the IVF and pregnancy rate in poor responders.

Comparison of sperm motility between the swim-up and swim-down methods.

The objective of this study was to compare two methods for the extraction of high motility sperm; the swim-up and swim-down techniques. The result showed that both methods produced greater sperm motility than the original semen. The motility of the sperm was lower in the swim-down method compared with the swim-up method (65.5+11.2% vs 76.5+10.1%; p<0.01).

A comparison of swim-up and simple swim-up methods for the extraction of high motility sperm.

The objective of this study was to compare two methods for the extraction of high motility sperm; swim-up and simple swim-up technique. The results were comparable in concentration, motility and morphology.

Semen parameters retrieved by electroejaculation in spinal cord injured Thai men: Preliminary report.

Semen characteristics from seven spinal injured Thai men retrieved by electroejaculation were studied at Spinal cord injury unit and Infertility unit, Siriraj hospital. The mean age of the subjects was 24.7 years. Three cases had sperm count within normal limit ( > 20x106/c.c. ) and oligospermia in three cases. One case had azoospermia. All had low motility or no motility at all. All had leukospermia ( > 1x106/c.c. ) except one case. This study shows the change in semen parameters and may help for planning the management of spinal cord injured men.

Conservative management for cervical pregnancy: A case report.

Cervical pregnancy is a rare, life-threatening from of ectopic pregnancy. Early diagnosis and conservative treatment can preserve the uterus, especially in young women. This report discusses a case of cervical pregnancy treated by combined conservative methods.

Fertilization rate during intracytoplasmic sperm injection procedure comparing 6 and 12 O’clock polar body position.

A Prospective study was designed to compare fertilization rate between the . and 12 o’clock position of the polar body during the intracytoplasmic sperm injection (ICSI) procedure. A total of 128 oocytes were injected by placing the first polar body at 6 o’clock and 12 o’clock alternately. Normal fertilization rates were 70.31 and 71.87 percent respectively. There was no statistical significance between the two groups.

The length of the follicular phase influences normal fertilization rates in assisted reproduction.

Factors affecting normal fertilization rates (NFR) were studied in 1,776 IVF patients having 3383 treatments during 1990-1992. Interestingly, the longer the follicular phase (LFP) the higher the fertilization rate: LFP <12, 12, 13, and >13 days, NFR 49.6%, 53.8, 53.9 and 56.1% respectively. Higher fertilization rates were also related to normal semen analysis results, older females, the use of frozen husband and donor sperm, the diagnosis of tubal disease and the use of ovarian stimulation protocols other than clomiphene citrate plus human menopausal gonadotrophin.

Basal body temperature chart as a guide for donor insemination.

The use of BBT in a single donor insemination and the conception rate according to cycle day was studied. For 107 such cycles, inseminations were performed on day 0 in 21.5% of cycles, on days-1,+1 and –2 in 17.8%, 16.8% and 13.1% respectively. The overall pregnancy rate achieved was 44%. The success rate per cycle was 15%, and the highest success rates were obtained on day 0 (43.7%) and day –1 (31.2%). No pregnancies occurred when insemination was done before day -3 and beyond day +1. In conclusion BBT provides a reasonable guide to the 2-to 3-day period on either side of the nadir in donor insemination.