ABSTRACT
Objective: Evaluating the effects of Povidone- Iodine against the surgical site infection in post- appendectomy wound infection
Study design: Randomized clinical trial
Place and duration: Department of Surgery, Isra University Hospital Hyderabad from January 2016 to December 2017
Subjects and Methods: Patients of acute appendicitis with classical clinical presentation were selected according to inclusion and exclusion criteria. 60 patients were those in which wound was irrigated with 1% povidone-iodine solution versus 60 patients in whom wound not irrigated with it before skin closure. Data was analyzed on SPSS 22.0 using Student t-test and Chi- square test respectively. Data was analyzed at 95% confidence interval [P=0.05]. P-value of =0.05 was taken statistically
Results: Mean +/- SD age of control and cases was noted as 22.5 +/- 7.5 and 23.5 +/- 6.5 years respectively [P=0.86]. Male and female population in control and cases were noted as 45 [75%] and 15 [25%] and 47 [78.33%] and 13 [21.66%] respectively [P >0.05]. Grade 4 pus discharging wound infection was noted in 3.33% in control compared to 1.66% in cases [P= 0.87]. Normal wound healing [grad 0] was noted in 37 [61.6%] and 43 [71.6%] of control and cases respectively. In control grade 1-4 lesions were noted in 38.4% compared to 28.4% in cases [P < 0.05]
Conclusion: Simple irrigation of appendectomy wound with 1% povidone- iodine significantly prevents against the surgical site infection and pus formation