A Case of Granular Cell Tumor in Form of Ciliary Body Tumor

PURPOSE:To report a case of a granular cell tumor in the form of cilliary body tumor. CASE SUMMARY: A 42-year-old women visited our clinic with blurred vision of the right eye, which began was 1 month earlier ago. Her medical history was unremarkable. Slit-lamp examination revealed a ciliary body tumor and complicated cataract due to a mass lesion. For treatment, an excisional biopsy of the ciliary body tumor and phacoemulsification were performed. The pathologic finding confirmed the diagnosis of a granular cell tumor. There was no evidence of a recurrent lesion of the tumor at the 6-month postoperative follow-up. CONCLUSIONS: We confirmed a granular cell tumor in the form of a cilliary body tumor based on pathologic findings.

The Effect of Artificial Tear Application on Central Corneal Thickness in Dry Eye

PURPOSE: To examine the effect of artificial tear use on central corneal thickness (CCT) in dry and normal eyes as a standard diagnosis for indicating dry eye. METHODS: Thirty eyes of 30 patients with symptomatic dry eyes and 25 eyes of 25 controls were examined in this study. Artificial tear therapy consisting of 6 drops/day was given to both groups for 2 weeks. The CCT was measured with ultrasonic pachymetry before and after the therapy. Results were analyzed with a paired t-test and Mann-Whitney U-test. RESULTS: The mean CCT in the dry eye group before and after the 2 weeks of therapy was 528.9+/-17.3 micrometer and 556+/-25.3 micrometer, respectively, which is an increase of 5.28% (27.1+/-9.2 micrometer, p<0.01). The mean CCT in the control group before and after the 2 weeks of therapy was 546.3+/-36.5 micrometer and 549.6+/-39.3 micrometer, respectively, which is an increase of 0.61% (3.3+/-2.8 micrometer, p=0.08). CONCLUSIONS: The CCT in the dry eye group increased significantly compared to the eyes in the control group after use of artificial tears. The results indicate that the increase could be used as a standard in the diagnosis and follow-up of dry eyes, and the increase in thickness should be considered in intraocular pressure measurements as well as in refractive surgical procedures.

A Case of Melanocytoma of the Ciliary Body

PURPOSE: To report a patient with melanocytoma of the ciliary body. METHODS: A 52-year-old woman, who transferred from a private ophthalmic clinic to our hospital after a cataract operation due to a mass behind the iris, was evaluated. The patient had a dark brown mass with a smooth surface confirmed by ultrasonogram, CT, and MRI. The mass was removed by en bloc resection. RESULTS: The tumor had a gross finding of a dark brown, soft, and smooth surface 0.5x0.5x0.5 cm in size. Histopathologic examination revealed a melanocytoma originating in the ciliary body. There was no evidence of metastasis. CONCLUSIONS: A very rare ciliary body melanocytoma was discovered with a good surgical result obtained by its removal.

Factors Affecting the Ocular Response Analyzer Parameters in Normal Korean

PURPOSE: To identify the normal range of factors which can be measured with Ocular Response Analyzer (ORA, Reichert Inc., Depew, NY, USA) in normal Korean, and to analyze factors affecting ORA by measuring intraocular pressure (IOP) of noncontact tonometer (NCT) and central corneal thickness (CCT). METHODS: Three hundred and one normal Korean subjects who did not have specific ophthalmological diseases and surgeries in the past were recruited for this study. Corneal hysteresis (CH), corneal response factor (CRF), corneal-compensated IOP (IOPcc), and Goldmann correlated IOP (IOPg) were measured using ORA. In addition, IOP of NCT and CCT were measured and the results and factors analyzed. RESULTS: The mean CH measured among normal Korean subjects in this study was 10.70 mmHg. The mean CRF was 10.40 mmHg. CH and CRF were significantly higher in the juvenile group. IOPcc and IOPg as measures of IOP using the ORA had significant correlation with IOP of NCT. In particular, IOPcc appeared to be independent of CCT. CONCLUSIONS: CH and CRF were different according to age, indicating a difference in biomechanical properties of the cornea. In particular, IOPcc is more important as it is independent of corneal thickness and should be compensated in general measurements of IOP reflecting biomechanical properties.

Clinical Effects of Various Antiinflammatory Therapies in Dry Eye Syndrome

PURPOSE: To evaluate the therapeutic effect of cyclosporin A, corticosteroid, autologous serum in patients with severe dry eye syndrome. METHODS: Patients (72 eyes) with severe dry eye syndrome were classified into four groups were treated for 3 months. Each group was treated with 0.05% cyclosporin A, 1% rimexolone, 20% autologous serum, and artificial tears. Before and after treatment (2, 4, 8, 12 weeks), Ocular Surface Disease Index (OSDI), tear film break-up time (BUT), Schirmer test, corneal sensitivity, and lissamine green staining score were measured. RESULTS: After treatment, OSDI, tear film BUT, Schirmer test, corneal sensitivity, and the lissamine green staining score were improved in groups using cyclosporin A, autologous serum and corticosteroid(p0.05). CONCLUSIONS: Antiinflammatory theraphy is more effective than the conventional symptomatic theraphy in patients with severe dry eye syndrome.