ABSTRACT
Food-dependent exercise-induced anaphylaxis (FDEIA) is a specific variant of exercise-induced anaphylaxis that requires both vigorous physical activity and the ingestion of specific foods. In particular, it is rare occurrence for FDEIA to be associated with meat in Korea. A 15-year-old female had generalized urticaria, dyspnea, severe cough, headache, dizziness, and vomiting after singing and dancing for 1 hour and after ingesting grilled pork. Skin prick tests showed a strong positive reaction to pork, whereas the results of an oral food challenge and exercise provocation tests were negative. However, the exercise provocation test after pork ingestion showed a positive reaction manifested by generalized urticaria, cough, mild dyspnea, and a 23% decreased peak expiratory flow rate. Three allergens to pork (67 kDa, 90 kDa, and 15 kDa) reacted with the patient's serum on immunoglobulin E immunoblotting. We report a case of pork-dependent exercise-induced anaphylaxis in a patient who was sensitive to pork.
Subject(s)
Adolescent , Female , Humans , Allergens , Anaphylaxis , Cough , Dancing , Dizziness , Dyspnea , Eating , Food Hypersensitivity , Headache , Immunoblotting , Immunoglobulin E , Immunoglobulins , Korea , Meat , Motor Activity , Peak Expiratory Flow Rate , Singing , Skin , Urticaria , VomitingABSTRACT
PURPOSE: We investigated the complexities of benign convulsions associated with gastroenteritis in children. METHODS: We selected children diagnosed as afebrile convulsion with acute gastroenteritis from June 2006 to May 2008 who had been admitted to the Kwandong Medical College Myongji Hospital. We investigated clinical features, EEGs, and brain imaging results for patients exhibiting complex-type seizures (Group B) and compared the data with that from patients with simple seizures (Group A). The statistical significance between the two groups was subsequently examined. RESULTS: A total of 43 patients showed afebrile benign convulsions with acute gastroenteritis, and 18 patients were diagnosed as CwG (benign convulsions with acute gastroenteritis). The median age of Group B was 26.3 month which was significantly higher than that of Group A (P < 0.05). The gender ratio was 3.5 times more in higher female of Group A compared to Group B (P < 0.05). The most common type of seizure in both groups was generalized tonic convulsions, and there were no statistical differences in the laboratory results between the two groups. Further, Group B showed more frequent abnormal findings than Group B with respect to EEG and brain imaging studies (P < 0.05). All of the abnormal findings in brain imaging studies were structural abnormalities unrelated with CwG, and patients with abnormal EEGs showed no recurrent seizure attacks and exhibited normal follow-up EEGs after discharge. CONCLUSION: CwG with complex-type seizure frequently occurred in children older than three years of age regardless of gender, and also in patients with underlying CNS diseases. Regardless of recurrent seizures or seizures lasting more than 15 minutes, patients diagnosed as CwG would receive a favorable prognosis.
Subject(s)
Child , Female , Humans , Central Nervous System Diseases , Electroencephalography , Follow-Up Studies , Gastroenteritis , Neuroimaging , Prognosis , SeizuresABSTRACT
PURPOSE: We investigated the change of antibody titer to measles, mumps and rubella according to age after vaccination. METHODS: The IgG antibody titers to measles, mumps and rubella were tested on the residual serum from patients aged 7-20 years old after routine laboratory testing in the hospital with informed consent from the parents. RESULTS: Antibody to measles was present in 275 cases out of 408 cases with a positive rate of 67.4%, the mean IgG titer was 2.77+/-1.18 Index. Antibody to mumps was present in 112 cases out of 408 cases with a positive rate of 27.5%, the mean IgG titer was 2.08+/-1.29 Index. Antibody to rubella was present in 367 cases out of 408 cases with a positive rate of 90.0%, the mean IgG titer was 60.46+/-63.47 IU/mL. CONCLUSION: It is important to maintain a high rate of vaccination coverage in order to prevent an outbreak of measles, mumps, or rubella. It is also important to stress the maintenance of vaccination records for further reference.