Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
1.
Korean Journal of Perinatology ; : 244-249, 2005.
Article in Korean | WPRIM | ID: wpr-19559

ABSTRACT

OBJECTIVE: We performed uterine artery doppler flow velocity waveforms between 20~24 weeks of gestation to access the screening properties for predicting pregnancy-induced hypertension or intrauterine growth retardation in general population. METHODS: Total 458 normal pregnant women were enrolled in this study. The abnormal uterine artery doppler flow velocity waveforms was defined that systolic/diastolic ratio is greater than 2.6 or diastolic notch waveforms are seen. RESULTS: The incidence of PIH and IUGR among study population was 3.5% and 3.5%, respectively. The incidence of PIH in normal and abnormal uterine artery Doppler flow velocity waveforms group were 2.0% and 11.4%, and those of IUGR were 3.4% and 4.2%, respectively. The incidence PIH or IUGR among abnormal doppler group was 14.2%, which was higher than in normal group of 5.4%. This method had a sensitivity of 34.3%, a specificity of 86.1% and positive predictive value of 15.7% for the prediction of PIH and IUGR. CONCLUSION: Although abnormal uterine artery doppler flow velocity waveforms is associated with an increased risk of PIH or IUGR, the lowered positive predictability lead to apply the follow-up examination or standardization of doppler ultrasonography.


Subject(s)
Female , Humans , Pregnancy , Fetal Growth Retardation , Follow-Up Studies , Hypertension, Pregnancy-Induced , Incidence , Mass Screening , Pregnancy Trimester, Second , Pregnant Women , Sensitivity and Specificity , Ultrasonography, Doppler , Uterine Artery
2.
Korean Journal of Obstetrics and Gynecology ; : 1214-1217, 2002.
Article in Korean | WPRIM | ID: wpr-87504

ABSTRACT

Antiestrogens have been widely used in the treatment of breast cancer patients. Although tamoxifen is one of the most prevalent antiestrogens, some reported its hepatocarcinogenic effects and the long-term treatment may increase the risk of endometrial and gastrointestinal cancer. Toremifene is an interesting new antiestrogen and have a similar antitumor efficacy as tamoxifen, with less side-effect including less uterotrophic effect compared to tamoxifen, in mice. we report a case of endometrial polyp which were associated with toremifene use, in postmenopausal woman with breast cancer, with a brief review of literature.


Subject(s)
Animals , Female , Humans , Mice , Breast Neoplasms , Estrogen Receptor Modulators , Gastrointestinal Neoplasms , Polyps , Tamoxifen , Toremifene
SELECTION OF CITATIONS
SEARCH DETAIL