ABSTRACT
Purpose@#To compare the vessel density (VD) and foveal avascular zone (FAZ) area using four different optical coherence tomography angiography (OCTA) images. @*Methods@#This prospective study analyzed the OCTA images of consecutive healthy subjects using Plex-Elite (Carl Zeiss), DRI OCT-1 Atlantis (Topcon), AngioPlex (Carl Zeiss), and Spectralis OCTA (Heidelberg Engineering). The VD and FAZ areas were calculated using the OCTA images with a 3 x 3 mm2 volume scan pattern centered on the fovea. @*Results@#The VD (%) of the superficial capillary plexus (SCP) and deep capillary plexus (DCP) were different using the four devices: Plex-Elite (42.17 ± 2.79, 43.71 ± 2.36), DRI OCT-1 Atlantis (28.70 ± 2.87, 30.27 ± 3.02), AngioPlex (28.32 ± 6.68, 33.33 ± 5.44), and Spectralis OCTA (27.86 ± 4.13, 28.54 ± 3.14), respectively; p 0.05), but the FAZ area had positive correlations using the four devices (all, p < 0.001). @*Conclusions@#The four OCTA devices provided different VD and FAZ areas, so these differences should be considered in analyzing OCTA images.