Clinical Efficacy of Piracetam in the Management of Acute Stroke and Post-Stroke Sequelae: An Expert Panel Review and Opinion

Stroke is a major cause of death worldwide. Prompt treatment and decision-making is essential for good outcomes. The two major therapeutic approaches for acute ischemic stroke are thrombolytics and neuroprotectants. Piracetam, a nootropic drug aims to increase cerebral blood flow, enhance oxygen extraction, restore membrane fluidity and modulate neurotransmission. Likewise, citicoline has been shown to positively influence cerebral plasticity and neurorepair processes. The present article aims to offer insights on the current management of acute stroke and to position piracetam and its combination with citicoline in the management of acute stroke and post-stroke sequelae based on an expert panel discussion.

Genito-perineal raphe cyst in an infant: a case report and review of literature

Canaliform genitoperineal raphe cyst is an unusual entity. satisfactory recovery. Microbiology of cyst fluid confirmed A three-month-old infant presented with a cordlike white bacteroides infection. Management and clinical presentation swelling of one week duration. Surgical excision resulted in is discussed along with review of literature

Splenogonadal fusion in a boy: case report and review of literature

We report an unusual case of splenogonadal fusion in a four-year-old boy with history of bilateral undescended testes. He had presented to us when he was one month old with an empty scrotum. On clinical examination he had bilateral undescended testes. The right testis was palpable in the inguinal region and the left was not palpable. No other anomaly was detected on clinical examination. Right orchidopexy was done at three years of age. Left impalpable testis was subsequently managed by left groin exploration which revealed no testis. Hence exploratory laparotomy was done. An intrabdominal left testis was found which had two abnormal-looking fleshy masses on its superior pole. Excision biopsy of these nodules was done and first stage orchidopexy was performed as it was difficult to mobilize the testis up to the left scrotum. Biopsy of the nodules revealed Splenogonadal fusion; hence we were justified in saving the testis. Second-stage orchidopexy was done after three months to fix the testis in the left scrotum

Idiopathic perforation of caecum in a neonate: case report

We report perforation of the caecum without a demonstrable cause in a three days old, healthy, male neonate. He presented with abdominal distention and constipation. Abdominal radiograph showed massive pneumoperitoneum. Caecal perforation was found on exploration. The perforation was closed and a protective proximal ileostomy was performed. The rest of the large intestine and small bowel appeared normal. Hirschsprung's disease was ruled out by multiple seromuscular biopsies. At a three monthly followup after closure of ileostomy, the baby showed normal weight gain without any symptoms