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1.
Article in English | IMSEAR | ID: sea-139863

ABSTRACT

Mechanical removal of the biofilm and adjunctive use of antibacterial disinfectants or various antibiotics have been conventional methods of the periodontitis therapy. There has been an upsurge of bacterial strains becoming resistant due to the injudicious use of antibiotics, recently. As a result there is pronounced interest and keenness in the development of alternate antimicrobial concepts. As the scientific community seeks alternatives to antibiotic treatment, periodontal researchers have found that photodynamic therapy (PDT) is advantageous to suppress anaerobic bacteria. Hence, PDT could be an alternative to conventional periodontal therapeutic methods. This review elucidates the evolution and use of photo dynamic therapy. The application of photosensitizing dyes and their excitation by visible light enables effective killing of periodontopathogens. Even though PDT is still in the experimental stages of development and testing, the method may be an adjunct to conventional antibacterial measures in periodontology. PDT application has an adjunctive benefit besides mechanical treatment at sites with difficult access. Necessity for flap operations may be reduced, patient comfort may increase and treatment time decrease. Clinical follow-up studies are needed to confirm the efficacy of the procedure.


Subject(s)
Bacteria, Anaerobic/drug effects , Biofilms/drug effects , Drug Resistance, Microbial , Furcation Defects/drug therapy , Humans , Periodontitis/drug therapy , Photochemotherapy , Photosensitizing Agents/pharmacology , Photosensitizing Agents/therapeutic use
2.
Article in English | IMSEAR | ID: sea-51841

ABSTRACT

This study compared the anti-inflammatory efficacy of Triclosan and Flurbiprofen in a gel form on clinical parameters of moderate gingivitis cases. The study comprised of 100 sites from 16 volunteers and used split mouth technique. 0.3% Triclosan/0.3% Flurbiprofen gels applied intracrevicularly once daily for one week. Clinical parameters like Plaque index, Gingival index and Bleeding index scores were recorded at 0 day, 4th day and 8th day. The obtained results showed significant reductions in clinical parameters from baseline to 8th day. This indicates local delivery of 0.3% Triclosan/0.3% Flurbiprofen gel can be used as an anti-inflammatory agents either alone or as an adjunct to scaling in periodontal therapy.


Subject(s)
Adolescent , Adult , Anti-Infective Agents, Local/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Dental Plaque Index , Female , Flurbiprofen/administration & dosage , Gels , Gingiva , Gingivitis/drug therapy , Humans , Injections , Male , Periodontal Index , Triclosan/administration & dosage
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