ABSTRACT
A histopathologically proven case of cerebral toxoplasmosis in a young HIV positive patient has been presented. The clinical problems in management are highlighted.
Subject(s)
Adult , Fatal Outcome , HIV Infections/complications , Humans , Male , Tomography, X-Ray Computed , Toxoplasmosis, Cerebral/pathologyABSTRACT
Partial trisomy of chromosome 10q is a very rare condition with only four cases having been reported int he literature. This report describes a neonate with symmetric growth retardation and multiple dysmorphic features, in whom G-banded chromosomal analysis revealed a partial trisomy of chromosome 10q (q2.4-q ter). The father was diagnosed as a carrier of a balanced translocation with a karyotype of 46, XY t(10.3) (q2.4L : pter). In patients with a bad obstetric history, genetic counselling prior to a new conception cna aid in early prenatal diagnosis of fetuses with recurrent chromosomal abnormalities by means of fetal tissue sampling.
Subject(s)
Adult , Chromosome Banding , Chromosomes, Human, Pair 10 , Female , Fetal Growth Retardation/genetics , Genetic Carrier Screening , Humans , Infant, Newborn , Karyotyping , Pedigree , Pregnancy , Trisomy , Ultrasonography, PrenatalSubject(s)
Abnormalities, Multiple , Chromosomes, Human, Pair 11 , Chromosomes, Human, Pair 12 , Heterozygote , Humans , Infant, Newborn , Male , Pedigree , Translocation, Genetic , TrisomyABSTRACT
Fibrocalculous pancreatic diabetes (FCPD) is a form of diabetes seen in tropical countries. It is secondary to chronic, calcific, non-alcoholic pancreatitis. FCPD is usually a disease of youth. This paper reports on two elderly onset cases of FCPD. Macrovascular complications are usually rare in FCPD patients. These two patients had evidence of macrovascular diseases probably due to the older age group of the patients.