ABSTRACT
OBJECTIVE: To observe the frequency and various risk factors associated with restless legs syndrome [RLS] in haemodialysis [HD] patients and to evaluate various factors associated with RLS
DESIGN OF THE STUDY: Cross-sectional study
PLACE and DURATION: Department of Nephrology, dialysis unit, Isra University Hospital and Hirani Dialysis Centre, Hyderabad. Duration from 15-5-2011 to 27-7-2012
METHODS: The criteria of the international restless study group used to diagnose RLS, while John Hopkins restless legs 4 points severity scale was used to assess severity of RLS. All patients were reinterviewed and clinically examined by qualified neurologist. In this study 100 patients were included from two dialysis centre. The following data were collected: age, sex, duration of dialysis, cause of end stage renal failure, BUN, creatinin, serum sodium, serum potassium, serum calcium, serum phosphates, Hemoglobin, ferritin, albumin, and PTH level
RESULTS: The clinical and biochemical data of 100 patients from 137 were available. RLS was present in 32 patients [32%]. Mild 16 [50%], moderate 12 [37.5%] and severe R.L.S was present in 4 [12.5%] patients respectively. We found association with increasing duration of dialysis and high calcium
CONCLUSION: The frequency of R.L.S in our dialysis patients is 32%. Results showed RLS is associated with increasing duration of dialysis and high calcium. More studies are required to see association of RLS with other factors like female gender, diabetes, and low iron
ABSTRACT
OBJECT: to find out frequency of various acute complications during haemodialysis
STUDY DESIGN: Prospective study
PLACE and DURATION: The haemodialysis unit of Isra University Hospital, Hyderabad, over period of 27 months, November 2010 to January 2013
METHODOLOGY: The Patients of end stage renal disease and advance acute renal failure provided dialysis and observed for any acute complication during haemodialysis
RESULT: In total 176 patients, male were 166 [66%] and female were 60 [34%]. A total of 2171 haemodialysis session were performed. Hypotension was observed during 12 [5.84%] dialysis session, Hypertension in 77 [3.54%] session. Vomiting in 70 [3.22%], muscles cramps in 67 [3.08%], fever in 33 [1.52%], Headache in 20 [0.9%] and chest pain 21 [0.96%] dialysis sessions
CONCLUSION: Haemodialysis is a life saving treatment procedure but it is not without complications and frequent complication are hypotension, Hypertension, Muscle cramps and vomiting
ABSTRACT
OBJECTIVE: To determine the in-hospital outcome of Native Valve Endocarditis patients and associated complications
STUDY DESIGN, PLACE AND DURATION: Hospital based prospective study, Department of Cardiology, Liaquat University Hospital Hyderabad from July 2005 to December 2007
PATIENTS AND METHODS: 56 consecutive patients, who presented with fever, joint pain, dyspnoea, history of Rheumatic fever, previous history of IE, history of I/V drug abusiveness were studied by history, physical examination, 3 blood samples were taken and sent to the laboratory for culture and sensitivity. All patients were evaluated by Doppler echocardiography on day 1, at 14 day, at one month and on 6th week of treatment. Empiric treatment was started on admission and later adjusted according to culture and sensitivity. Descriptive and inferential statistical analysis was performed using SPSS version 16.0
RESULTS: Males out numbered females with ratio 37[66.1%] / 19[33.9%]. Definite vegetation was found in 40/56 [71.4%]; but definite culture positive cases were 30/56 [53.6%]. Complete improvement was seen in 32[57.1%], 08[14.3%] patients died during the course of treatment in hospital, 10[17.9%] were referred for surgery and 06[10.7%] patients developed recurrent episode of infective endocarditis. 13/56[23.2%] patients developed congestive heart failure, recurrent episodes of fever in 8[14.3%] and valvular regurgitation 6[10.7%] cases
CONCLUSION: Our study showed that native valve infective endocarditis is not un common
Early diagnosis and treatment can help in improving morbidity and mortality, overall outcome and can reduce devastating complications associated with infective endocarditis. Patients who require surgical intervention like large vegetations or abscess should be referred for surgery as early as possible to avoid further complications