Novel Coronavirus (2019-nCoV) Outbreak- Break the Chain

Novel coronavirus has recently gained attention of the global community after it was first reported from Wuhan, China. It has been declared as global health emergency with implications to all people. Droplets of bodily fluids, such as saliva or mucus, from an infected person are dispersed in the air or on surfaces by coughing or sneezing and could be the main source for the further spread of infection. All healthcare professionals including Dental Surgeons should help to prevent transmission of this deadly virus. It’s a virus affecting both human and animals and spreads from animals and person to person in close proximity, similar to other respiratory illnesses, such as the flu. This review article mainly highlights the types, epidemiology, transmission and addresses the implications of 2019 n-CoV from the health professionals perspective and discusses the necessary preventive precautions that should be strictly followed in a dental setup so as to prevent further spread of infection.

Kallmann's syndrome.

Kallmann's syndrome is a rare genetic disorder due to abnormal migration of olfactory axons and gonadotropin releasing hormone producing neurons, characterized by hypogonadism and anosmia. The prevalence of Kallmann's syndrome is 1:10,000 to 1:60,000 with a male to female ratio of 5:1. The inheritance of Kallmann's syndrome may be X-linked, autosomal recessive or autosomal dominant with variable penetrance, mutation involving KAL-1 and KAL-2 gene respectively. We report a case of Kallmann's syndrome in a 19-year-old boy with characteristic clinical, biochemical and MRI findings.

Osteopetrosis with Arnold Chiari malformation type I and brain stem compression.

Osteopetrosis is a collective term for a range of sclerosing bone diseases resulting from an absence or defective function of osteoclasts. The clinical expression is variable and includes skeletal, hematological and neurological manifestations. The common neurological manifestation includes cranial neuropathies involving optic, cochlear, facial and trigeminal nerves. Spastic quadriplegia occurring as a result of brain stem compression in osteopetrosis is uncommon. The association of Type 1 Arnold Chiari malformation with osteopetrosis resulting in brain stem compression syndrome is an extremely rare entity.