ABSTRACT
AIMAim of this study was to evaluate Predicted 4 and 10-years risk of major CVD of DMpatients.METHODSCross-sectional study included 80 (40 male and 40 female) DM patients with meanage 66.32 ±7.94 years old. Predicted 4-year risk of major CVD was calculated by usingADVANCE Risk Engine of the George Institute for Global Health, Australia. Ten parameters(age at diagnosed diabetes, duration of diabetes, sex, atrial fibrillation, retinopathy,HbA1C, pulse pressure, treated hypertension, albuminuria and Non HDL-cholesterol)were used for risk calculation. Predicted 10-year risk of major CVD was calculated byusing WHO/ISH risk prediction chartrs Parameters (age, sex, systolic blood pressure, totalcholesterol, smoking) were used for risk calculation.RESULTSOur study relieved that average of diagnosis diabetes was 54.98±9.37 years oldand mean diabetes duration was 11.35±7.46 years. DM patient with atrial fibrillation,retinopathy and treated hypertension were 0(0%), 20(16%) and 77.5(62%). Mean HbA1C,microalbuminuria and Non HDL cholesterol were 7.74±1.5%, 49.99±94.02 mg/l and3.61±1.08 mmol/l. DM patients with 20% Predicted 4-year riskof major CVD were 64( 80%), 12 (15%) and 4(5.0%). Age (p30% Predicted 10-year risk of major CVDwere 44 (55%), 20 (25%), 6 (7.5.0%) and 10 (12.5%). Age (p=0.008), total cholesterol(p=0.001), systolic blood pressure (p=0.001) and treated hypertension (p=0.023) wererisks for Predicted 10-year risk of major CVD.CONCLUSIONSAmong the diabetic patients 80% have a low, 15% have a moderate and 5.0%have a high Predicted 4-year risk of major CVD. Age (p<0.042), age at diagnoseddiabetes (p=0.013), , duration of diabetes (p=0.045), total cholesterol (p<0.027)Microalbuminuria (p<0.001) and retinopathy (p=0.028) were risks for Predicted 4-yearrisk of major CVD. Among the diabetic patients 55% have a low, 25% have a moderate,7.5% have a high and 12.5% have a very high Predicted 10-year risk of major CVD. Age(p=0.008), total cholesterol (p=0.00, systolic blood pressure (p=0.001) and treatedhypertension (p=0.023) were risks for Predicted 10-year risk of major CVD.
ABSTRACT
Background: Since life style of the nation has changed, the prevalence of T2DM has steadily increased. According to T2DM related studies, estimated number of people with diabetes is 80.000 in Mongolia. Despite this, total number of diabetic patients registered in Mongolia is only 7000. Thus, approximately 90% of people with diabetes are undiagnosed and untreated.Objective: to assess anthropometric and laboratory parameters of newly diagnosed patients with T2DM.Materials and Methods: It was cross sectional study included 133 patients with type 2 diabetes newly diagnosed at the district hospital of Ulaanbaatar. We measured height, weight and waist circumference and analyzed body fat by bio-impedance analyzer machine. Fasting blood glucose, HbA1c, triglyceride, HDL-C, LDL-C were determined by methods of laboratory in venous plasma. We defined as subjects with metabolic syndrome used the IDF new definition of 2009.Results: 44.4% of all participants were male and 55.6% were female and mean age of all participants was 49.1±8.5. According to BMI 85.7% of patients was obese and overweight and 84.2% of patients identified central obesity by measuring waist circumference. In analyzing of body composition, 100% of all patients determined high body fat. 27.1% of men and 36.4% of women diagnosed arterial hypertension. According to HbA1c (%) level the 94% of patients determined 7.5 and above. The hypertriglyceridemia was 59.4%, hyper LDL-C was 76.7% and hypo HDL-C was 12% and increased LDL: HDL ratio was 8.1%. The prevalence of metabolic syndrome among the newly diagnosed patients with T2DM was 69.6%, male 66.1% and female 72.9%. Conclusion: Obese is major risk factor for T2DM in Mongolia. The study shows that assessing body fat is major identifying method of obese (p<0.03) and statistically significant association of high body fat mass with WC in diabetic patients (p<0.05). The prevalence of several risk factors of DM complications among newly diagnosed patients with T2DM is higher.