ABSTRACT
To assess the spectrum of microbes isolated from body fluids and secretions. It is a Descriptive: Observational study which was carried out from January 2010 at Taj Medical Complex Karachi. Pakistan. A total of three thousand and fifty six [3056] samples received in the laboratory of the Taj Medical Complex [both from indoor as well as outdoor patients] were included from both sexes satisfying the inclusion criteria. Included patients had a mean age of 40.5 years with female predominance. Nearly a third of included samples yielded any growth by microbial agents. Most commonly isolated pathogen was Klebsiella spp. followed by the Escherichia coli and Staphylococcus spp. The regular and meticulous monitoring of the pattern and distribution of microbial isolates can guide our choices in terms of empirical antibiotic therapies. Our study is a snapshot of the current microbiological occurrence